Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8078604 | 0.83 | SCN4A (0.41) | SCN4ASLC6A4EPHX1TAAR1LTA4H | |
| SCHEMBL28085523 | 0.81 | HRH1 (0.46) | SCN4ASLC6A4EPHX1TAAR1LTA4H | |
| SCHEMBL5679399 | 0.79 | HDAC3 (0.39) | SCN4ASLC6A4EPHX1TAAR1LTA4H | |
| SCHEMBL3227309 | 0.79 | SLC6A4 (0.41) | SCN4ASLC6A4EPHX1LTA4HMTNR1A | |
| SCHEMBL5674229 | 0.79 | ALDH1A1 (0.43) | SCN4ASLC6A4EPHX1LTA4HMTNR1A | |
| SCHEMBL4370604 | 0.78 | SLC6A4 (0.39) | SCN4ASLC6A4TAAR1LTA4HTSHR | |
| SCHEMBL3071330 | 0.78 | METAP2 (0.47) | EPHX1TAAR1PPARGPPARAMETAP2 | |
| SCHEMBL3229708 | 0.76 | LTA4H (0.44) | SLC6A4LTA4HSLC6A2SLC6A3KCNH2 | |
| SCHEMBL10584026 | 0.75 | SLC6A4 (0.41) | SLC6A4LTA4HTSHRKCNA3SLC6A2 | |
| SCHEMBL331604 | 0.75 | MTNR1A (0.47) | SLC6A4LTA4HMTNR1AMTNR1BMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846679-B1 | Process for preparing 1,3-disubstituted urea | SUMIKA FINE CHEMICALS CO LTD (JP) | 2000-09-06 | — | — | EP | disclosed |
| US-5902899-A | Process for preparing 1, 3-disubstituted urea | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1999-05-11 | — | — | US | disclosed |
| EP-0846679-A2 | Process for preparing 1,3-disubstituted urea | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1998-06-10 | — | — | EP | disclosed |