Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 9/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12467301 | 0.95 | P2RX7 (0.35) | P2RX7CYP2C9CYP1A2GRIA2F2 | |
| SCHEMBL795833 | 0.79 | CYP1A2 (0.34) | CYP2C9CYP1A2GRIA2 | |
| SCHEMBL15466205 | 0.78 | CYP1A2 (0.33) | P2RX7CYP2C9CYP1A2GRIA2 | |
| SCHEMBL807798 | 0.78 | TRAP1 (0.30) | — | |
| SCHEMBL794401 | 0.73 | EPHX2 (0.38) | P2RX7CYP2C9CYP1A2GRIA2EPHX2 | |
| SCHEMBL798081 | 0.73 | TRPV1 (0.31) | CYP2C9CYP1A2GRIA2 | |
| SCHEMBL794885 | 0.72 | P2RX7 (0.40) | P2RX7EPHX2 | |
| SCHEMBL15465826 | 0.72 | TRPV1 (0.37) | P2RX7CYP2C9CYP1A2GRIA2EPHX2 | |
| SCHEMBL795686 | 0.70 | NR1H2 (0.34) | CYP1A2GRIA2EPHX2 | |
| SCHEMBL15888062 | 0.70 | TRPV1 (0.35) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035011-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER CROPSCIENCE AG (DE) | 2012-03-22 | — | — | WO | disclosed |