Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.33 |
| ▸ | TACR1 | P25103 | 3/20 | 0.31 |
| ▸ | MASP2 | O00187 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL798081 | 0.93 | TRPV1 (0.31) | CYP1A2CYP2C9GRIA2TRPV1 | |
| SCHEMBL798082 | 0.89 | TRPV1 (0.31) | TRPV1 | |
| SCHEMBL795833 | 0.83 | CYP1A2 (0.34) | CYP1A2CYP2C9GRIA2TRPV1 | |
| SCHEMBL12467301 | 0.83 | P2RX7 (0.35) | CYP1A2CYP2C9GRIA2P2RX7 | |
| SCHEMBL807889 | 0.78 | P2RX7 (0.33) | CYP1A2CYP2C9GRIA2P2RX7 | |
| SCHEMBL794401 | 0.75 | EPHX2 (0.38) | CYP1A2CYP2C9GRIA2TRPV1P2RX7 | |
| SCHEMBL795686 | 0.74 | NR1H2 (0.34) | CYP1A2GRIA2TRPV1TACR1 | |
| SCHEMBL793870 | 0.74 | TSHR (0.40) | CYP2C9 | |
| SCHEMBL15465826 | 0.74 | TRPV1 (0.37) | CYP1A2CYP2C9GRIA2TRPV1P2RX7 | |
| SCHEMBL12467208 | 0.73 | TRPV1 (0.37) | CYP1A2CYP2C9GRIA2TRPV1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9375000-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-28 | — | — | US | disclosed |
| US-9375000-B2 | Pesticidal arylpyrrolidines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-28 | — | — | US | disclosed |
| US-20140046069-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-02-13 | — | — | US | disclosed |
| US-20140046069-A1 | PESTICIDAL ARYLPYRROLIDINES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140046069-A1 | PESTICIDAL ARYLPYRROLIDINES | DDT, ACHE, CAT | CYP1A2 28/4885CYP2C9 81/4885GRIA2 2227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.