SCHEMBL8079175

SCHEMBL8079175

CCc1nc2ccccc2nc1C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.64
SMN1; SMN2 Q16637 2/20 0.64
MAPT P10636 1/20 0.64
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
GAA P10253 1/20 0.47
KDM4E B2RXH2 4/20 0.46
MAPK1 P28482 2/20 0.46
HPGD P15428 2/20 0.46
HSD17B10 Q99714 2/20 0.46
LMNA P02545 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.44
PIM1 P11309 2/20 0.44
POLB P06746 1/20 0.44
RAD52 P43351 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
FABP3 P05413 1/20 0.43
FABP4 P15090 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL634980 0.81 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A
SCHEMBL11166760 0.80 ALDH1A1 (0.62) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A
SCHEMBL2024265 0.80 KDM4E (0.50) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A
SCHEMBL31456120 0.80 KDM4E (0.50) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A
SCHEMBL351486 0.80 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A
SCHEMBL29860539 0.80 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A
SCHEMBL28384025 0.78 ALDH1A1 (0.95) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A
SCHEMBL2491027 0.77 KDM4E (0.53) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A
SCHEMBL2407840 0.77 KDM4E (0.41) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A
Ammonia Solution, Strong SCHEMBL28585108 0.75 KDM4E (0.52) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP disclosed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP disclosed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP disclosed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP disclosed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US disclosed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US disclosed
US-3957805-A TREATMENT OF PAIN, MUSCLE SPASMS, ANXIETY, INFLAMMATION, OR TENSION AMERICAN CYANAMID COMPANY (US) 1976-05-18 US disclosed