Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of 2-Benzoylbenzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.71 |
| ▸ | CDC25B | P30305 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | CDC25A | P30304 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MYC | P01106 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL4372897 | 0.89 | ALDH1A1 (0.64) | AKR1C3POLBALDH1A1KDM4EALOX15 | |
| Phthalic Acid SCHEMBL5875380 | 0.89 | ALDH1A1 (0.64) | AKR1C3POLBALDH1A1KDM4EALOX15 | |
| Phthalic Acid SCHEMBL7634631 | 0.87 | ALDH1A1 (0.61) | AKR1C3POLBALDH1A1KDM4EALOX15 | |
| 2-Benzoylbenzoic Acid SCHEMBL11757908 | 0.87 | AKR1C3 (0.87) | AKR1C3CDC25BATMNR4A1POLB | |
| Benzophenone SCHEMBL27800808 | 0.85 | ALDH1A1 (0.64) | ATMALDH1A1KDM4ELMNAALOX15 | |
| Benzophenone SCHEMBL490746 | 0.85 | ALDH1A1 (0.64) | ATMALDH1A1KDM4ELMNAALOX15 | |
| Benzophenone SCHEMBL5804441 | 0.85 | ALDH1A1 (0.64) | ATMALDH1A1KDM4ELMNAALOX15 | |
| 2-Benzoylbenzoic Acid SCHEMBL30296847 | 0.84 | AKR1C3 (1.00) | AKR1C3CDC25BATMNR4A1POLB | |
| 2-Benzoylbenzoic Acid SCHEMBL76332 | 0.84 | AKR1C3 (1.00) | AKR1C3CDC25BATMNR4A1POLB | |
| Diethylamine SCHEMBL3323938 | 0.83 | ALDH1A1 (0.55) | AKR1C3CDC25BPOLBHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5917086-A | Purification process | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-06-29 | — | — | US | claimed |
| EP-0853078-A1 | Purification process of keto acids | Ciba SC Holding AG (CH) | 1998-07-15 | — | — | EP | claimed |
| EP-0853078-B1 | Purification process of keto acids | CIBA SC HOLDING AG (CH) | 2000-08-16 | — | — | EP | disclosed |
| US-5917086-A | Purification process | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-06-29 | — | — | US | disclosed |
| EP-0853078-A1 | Purification process of keto acids | Ciba SC Holding AG (CH) | 1998-07-15 | — | — | EP | disclosed |