Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Benzophenone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.54 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.52 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.52 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzophenone SCHEMBL490746 | 1.00 | ALDH1A1 (0.64) | ALDH1A1HPGDRAB9ALMNAL3MBTL1 | |
| Benzophenone SCHEMBL27800808 | 1.00 | ALDH1A1 (0.64) | ALDH1A1HPGDRAB9ALMNAL3MBTL1 | |
| Benzophenone SCHEMBL27572545 | 0.98 | ALDH1A1 (0.61) | ALDH1A1HPGDRAB9ALMNAL3MBTL1 | |
| Benzophenone SCHEMBL28002310 | 0.86 | ALDH1A1 (0.64) | ALDH1A1HPGDRAB9ALMNAL3MBTL1 | |
| Benzophenone SCHEMBL28239206 | 0.86 | ALDH1A1 (0.64) | ALDH1A1HPGDRAB9ALMNAL3MBTL1 | |
| Benzoic Acid SCHEMBL64441 | 0.86 | TSHR (0.64) | ALDH1A1HPGDRAB9ATDP1ATM | |
| Benzil SCHEMBL28793382 | 0.86 | CES2 (0.64) | ALDH1A1HPGDRAB9ATDP1SMN1; SMN2 | |
| Benzophenone SCHEMBL8089683 | 0.85 | ALDH1A1 (0.78) | ALDH1A1HPGDRAB9ALMNAL3MBTL1 | |
| SCHEMBL21505918 | 0.85 | SMN1; SMN2 (0.55) | ALDH1A1HPGDRAB9ALMNAL3MBTL1 | |
| 2-Benzoylbenzoic Acid SCHEMBL8079243 | 0.85 | AKR1C3 (0.71) | ALDH1A1RAB9ALMNAATMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105607422-B | Alkali-soluble resin, photosensitive resin composition containing same and application | 奇美实业股份有限公司 | 2019-11-12 | — | — | CN | disclosed |
| CN-105474096-B | Radiation-sensitive resin composition, resin film, and electronic component | 日本瑞翁株式会社 | 2019-11-12 | — | — | CN | disclosed |
| CN-105425542-B | Photosensitive resin composition for color filter and application thereof | 奇美实业股份有限公司 | 2019-10-18 | — | — | CN | disclosed |
| CN-108415221-A | Photosensitive resin composition and application thereof | 奇美实业股份有限公司 | 2018-08-17 | — | — | CN | disclosed |
| CN-101750892-B | Photosensitive resin composition and color filter formed by same | CHI MEI IND CO LTD | 2012-01-18 | — | — | CN | disclosed |
| WO-2006085494-A1 | FLAME-RETARDANT COMPOSITION FOR SOLDER RESIST AND USE THEREOF | SHOWA DENKO K.K. (JP) | 2006-08-17 | — | — | WO | disclosed |
| EP-1499915-A2 | EFFECTIVE REFRACTIVE INDEX CHIRPED BRAGG GRATINGS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2005-01-26 | — | — | EP | disclosed |
| EP-1493055-A2 | METHOD AND APPARATUS FOR HOMOGENOUS HEATING IN AN OPTICAL WAVEGUIDING STRUCTURE | E.I. du Pont de Nemours and Company (US) | 2005-01-05 | — | — | EP | disclosed |
| US-20040071401-A1 | Effective refractive index chirped bragg gratings | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-04-15 | — | — | US | disclosed |
| US-20040071386-A1 | Method and apparatus for homogeneous heating in an optical waveguiding structure | E. I. DU PONT DE NEMOURS AND COMPANY | 2004-04-15 | — | — | US | disclosed |
| WO-2003093885-A2 | EFFECTIVE REFRACTIVE INDEX CHIRPED BRAGG GRATINGS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-11-13 | — | — | WO | disclosed |
| WO-2003087922-A2 | METHOD AND APPARATUS FOR HOMOGENOUS HEATING OF AN OPTICAL WAVEGUIDING STRUCTURE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-10-23 | — | — | WO | disclosed |