Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024246 | 0.76 | HTR2C (0.56) | HTR2AHTR2CHTR2BCHRNB4CHRNA3 | |
| SCHEMBL8079228 | 0.75 | HTR2A (0.43) | HTR2AHTR2CHTR2BCHRNB4CHRNA3 | |
| SCHEMBL8079297 | 0.72 | HTR2A (0.43) | HTR2AHTR2CHTR2BCHRNB4CHRNA3 | |
| SCHEMBL20656815 | 0.72 | KDM1A (0.48) | HTR2CKDM1A | |
| SCHEMBL20656817 | 0.72 | KDM1A (0.48) | HTR2CKDM1A | |
| SCHEMBL8098685 | 0.72 | ALDH1A1 (0.46) | HTR2CKDM1A | |
| SCHEMBL9131537 | 0.71 | HTR2A (0.54) | HTR2AHTR2CHTR2BCHRNB4CHRNA3 | |
| SCHEMBL9131533 | 0.71 | HTR2A (0.54) | HTR2AHTR2CHTR2BCHRNB4CHRNA3 | |
| SCHEMBL29818204 | 0.69 | SLC9A1 (0.45) | HTR2CKDM1A | |
| SCHEMBL23923588 | 0.69 | HTR2A (0.56) | HTR2AHTR2CHTR2BCHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889024-B1 | Benzyloxy substituted aromatics and their use as fungicides and insecticides | ROHM & HAAS (US) | 2000-09-13 | — | — | EP | disclosed |
| US-5945557-A | PHENYL DERIVATIVES WHICH POSSESS A SUBSTITUTED CYCLOPROPYL MOIETY; USEFUL AGAINST POWDERY MILDEW, BLIGHT AND OTHER PLATN DISEASES; INSECTICIDES AGAINST SOUTHERN ARMYWORM, MEXICAN BEAN BEETLE AND SPIDER MITES, FOR EXAMPLE | ROHM AND HAAS COMPANY (US) | 1999-08-31 | — | — | US | disclosed |
| EP-0889024-A1 | Benzyloxy substituted aromatics and their use as fungicides and insecticides | ROHM AND HAAS COMPANY (US) | 1999-01-07 | — | — | EP | disclosed |