SCHEMBL8079514

SCHEMBL8079514

CC1=CCC(C2=C([Zr](Oc3ccc(F)cc3)Oc3ccc(F)cc3)C(=[Si](C)C)C=C2)=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6685547 0.70 ACHE (0.30)
SCHEMBL6686881 0.56 CYP1A2 (0.30)
SCHEMBL8156354 0.55
SCHEMBL6685552 0.55 USP2 (0.41)
SCHEMBL23160893 0.52
SCHEMBL6250597 0.49 SIGMAR1 (0.38)
SCHEMBL4005272 0.47 ALDH1A1 (0.52)
SCHEMBL7024215 0.46
SCHEMBL6617425 0.46 ALDH1A1 (0.64)
SCHEMBL8298 0.46

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1035138-A1 SOLID CATALYSTS FOR THE POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PRODUCTION OF OLEFIN POLYMERS THEREWITH MARUZEN PETROCHEMICAL CO., LTD. (JP) 2000-09-13 EP disclosed