Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8079473 | 0.90 | CALM1 (0.35) | SIGMAR1CALM1ALDH1A1 | |
| SCHEMBL8087900 | 0.83 | TP53 (0.40) | CALM1ALDH1A1 | |
| SCHEMBL8087972 | 0.78 | TLR7 (0.36) | SIGMAR1HPGDTLR8KCNH2HDAC3 | |
| SCHEMBL8087990 | 0.77 | SIGMAR1 (0.35) | SIGMAR1HPGDTLR8KCNH2HDAC3 | |
| SCHEMBL8088069 | 0.76 | TAAR1 (0.37) | SIGMAR1CALM1CNR2SMN1; SMN2ALDH1A1 | |
| SCHEMBL8086746 | 0.75 | ORAI1 (0.36) | SIGMAR1HSD11B1HPGDTLR8KCNH2 | |
| SCHEMBL8087987 | 0.72 | SIGMAR1 (0.39) | SIGMAR1HSD11B1HPGDTLR8KCNH2 | |
| SCHEMBL8079504 | 0.70 | SCD (0.33) | HPGD | |
| SCHEMBL6283235 | 0.70 | SCD (0.33) | HPGD | |
| Hydrochloric Acid SCHEMBL18585839 | 0.69 | CALM1 (0.37) | CALM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6046346-A | Production of alkali metal cyclopentadienylide and production of dihalobis (η-substituted-cyclopentadienyl) zirconium from alkali metal cyclopentadienylide | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2000-04-04 | — | — | US | disclosed |
| EP-0926150-A2 | Production of alkali metal cyclopentadienylide and production of dihalobis(eta-substituted-cyclopentadienyl) zirconium from alkali metal cyclopentadienylide | Honshu Chemical Industry Co. Ltd. (JP) | 1999-06-30 | — | — | EP | disclosed |