Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23027794 | 0.92 | LMNA (0.65) | LMNASMN1; SMN2L3MBTL1ALDH1A1HPGD | |
| SCHEMBL23027798 | 0.78 | LMNA (0.78) | LMNASMN1; SMN2L3MBTL1ALDH1A1HPGD | |
| SCHEMBL8656611 | 0.77 | PDE10A (0.51) | LMNASMN1; SMN2L3MBTL1ALDH1A1PKM | |
| SCHEMBL1205231 | 0.77 | PDE10A (0.55) | LMNASMN1; SMN2ALDH1A1PKMHSD17B10 | |
| SCHEMBL8091093 | 0.77 | HRH1 (0.54) | LMNASMN1; SMN2L3MBTL1ALDH1A1PKM | |
| SCHEMBL29263618 | 0.77 | HSD17B10 (0.77) | LMNAL3MBTL1ALDH1A1PKMMEN1 | |
| SCHEMBL28261467 | 0.76 | HSD17B10 (0.55) | LMNASMN1; SMN2L3MBTL1ALDH1A1PKM | |
| SCHEMBL27526928 | 0.76 | PDE10A (0.53) | LMNASMN1; SMN2L3MBTL1ALDH1A1PKM | |
| SCHEMBL7949941 | 0.76 | TDP1 (0.56) | L3MBTL1HSD17B10CYP1A2CYP2C9KDM4E | |
| SCHEMBL8091016 | 0.75 | HSD17B10 (0.42) | LMNASMN1; SMN2L3MBTL1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100404-A | Erythromycin compounds | HOECHST MARION ROUSSEL (FR) | 2000-08-08 | — | — | US | disclosed |
| US-5635485-A | Erythromycin compounds | ROUSSEL UCLAF (FR) | 1997-06-03 | — | — | US | disclosed |