Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8091020 | 1.00 | HSD17B10 (0.42) | HSD17B10PDE10ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL23027794 | 0.78 | LMNA (0.65) | HSD17B10PDE10ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8079751 | 0.75 | LMNA (0.55) | HSD17B10PDE10ALMNASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11480185 | 0.73 | POLB (0.43) | HSD17B10LMNASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL2438256 | 0.71 | PDE10A (0.58) | HSD17B10PDE10ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9116764 | 0.69 | PDE10A (0.56) | HSD17B10PDE10ALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL22121427 | 0.68 | GLS (0.59) | SMN1; SMN2L3MBTL1RAB9ANPC1MAPT | |
| SCHEMBL29263669 | 0.66 | HSD17B10 (0.69) | HSD17B10SMN1; SMN2ALDH1A1L3MBTL1RAB9A | |
| SCHEMBL7081163 | 0.64 | RAB9A (0.37) | HSD17B10SMN1; SMN2ALDH1A1L3MBTL1RAB9A | |
| SCHEMBL23027798 | 0.63 | LMNA (0.78) | HSD17B10PDE10ALMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100404-A | Erythromycin compounds | HOECHST MARION ROUSSEL (FR) | 2000-08-08 | — | — | US | disclosed |
| US-5635485-A | Erythromycin compounds | ROUSSEL UCLAF (FR) | 1997-06-03 | — | — | US | disclosed |