Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 6/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1831770 | 0.86 | CYP4F2 (0.46) | TSHRGAACYP4F2CYP4A11ACHE | |
| SCHEMBL351573 | 0.84 | TSHR (0.35) | TSHRACHEALDH1A1CYP3A4TDP1 | |
| SCHEMBL27940590 | 0.82 | TSHR (0.42) | TSHRGAACYP4F2CYP4A11ACHE | |
| SCHEMBL7617971 | 0.80 | TSHR (0.48) | TSHRACHECES2THRBALDH1A1 | |
| SCHEMBL351821 | 0.79 | TDP1 (0.34) | TSHRALDH1A1CYP3A4TDP1 | |
| SCHEMBL22383226 | 0.79 | CES2 (0.31) | CES2 | |
| SCHEMBL8079396 | 0.78 | TSHR (0.40) | TSHRGAACYP4F2CYP4A11ACHE | |
| SCHEMBL8537810 | 0.78 | TSHR (0.48) | TSHRCYP4F2CYP4A11ACHETHRB | |
| SCHEMBL22383117 | 0.78 | CES2 (0.45) | TSHRCYP4F2CYP4A11ACHECES2 | |
| SCHEMBL7622066 | 0.78 | TSHR (0.50) | TSHRACHECES2THRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675885-B1 | NOVEL RING OPENING MONOMERS | COMMW SCIENT IND RES ORG (AU) | 2000-09-06 | — | — | EP | disclosed |
| US-5665839-A | Ring opening monomers | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1997-09-09 | — | — | US | disclosed |
| EP-0675885-A4 | — | — | 1995-10-25 | — | — | EP | disclosed |
| EP-0675885-A1 | NOVEL RING OPENING MONOMERS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1995-10-11 | — | — | EP | disclosed |
| WO-1994014792-A1 | NOVEL RING OPENING MONOMERS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1994-07-07 | — | — | WO | disclosed |