SCHEMBL8080141

SCHEMBL8080141

CN(C)c1ccc(Nc2ccc(N)c3c2C(=O)C(C#N)=C(C#N)C3=O)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH3A1 P30838 1/20 0.37
▸ CA1 P00915 2/20 0.37
▸ CA2 P00918 2/20 0.37
▸ GAA P10253 6/20 0.36
▸ MEN1 O00255 6/20 0.36
▸ KMT2A Q03164 6/20 0.36
▸ RAB9A P51151 4/20 0.36
▸ L3MBTL1 Q9Y468 4/20 0.36
▸ MAPT P10636 4/20 0.36
▸ ALDH1A1 P00352 3/20 0.36
▸ MAPK1 P28482 3/20 0.36
▸ TDP1 Q9NUW8 3/20 0.36
▸ HPGD P15428 3/20 0.36
▸ LMNA P02545 3/20 0.36
▸ HTT P42858 3/20 0.36
▸ SMN1; SMN2 Q16637 3/20 0.36
▸ NPSR1 Q6W5P4 2/20 0.36
▸ GALR2 O43603 1/20 0.36
▸ NSD2 O96028 1/20 0.36
▸ KDM4E B2RXH2 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10875079 0.86 EGFR (0.44) GAAMEN1KMT2ARAB9AL3MBTL1
SCHEMBL10876607 0.85 GAA (0.43) GAAMEN1KMT2ARAB9AL3MBTL1
SCHEMBL4956416 0.82 GAA (0.50) GAAMEN1KMT2AL3MBTL1MAPT
SCHEMBL10874373 0.82 MAPT (0.46) ALDH3A1CA1CA2GAAMEN1
SCHEMBL10877705 0.82 DHODH (0.37) GAAMEN1KMT2AMAPTALDH1A1
SCHEMBL5870790 0.79 CTDSP1 (0.46) GAAMEN1KMT2ARAB9AL3MBTL1
SCHEMBL11047306 0.79 KMT2A (0.49) ALDH3A1CA1CA2GAAMEN1
SCHEMBL10875619 0.78 HPGD (0.42) CA1CA2MEN1KMT2ARAB9A
SCHEMBL20333934 0.75 MEN1 (0.46) CA1CA2GAAMEN1KMT2A
SCHEMBL14081299 0.73 THRB (0.59) MEN1KMT2ARAB9AL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7629997-B2 Information reader FUJIFILM CORPORATION (JP) 2009-12-08 — — US disclosed
US-20070292051-A1 INFORMATION READER FUJIFILM CORPORATION (JP) 2007-12-20 — — US disclosed
US-6136719-A Method and arrangement for fabricating a semiconductor device LSI LOGIC CORPORATION (US) 2000-10-24 — — US disclosed
US-5643700-A Photoresist composition and method of exposing photoresist SONY CORPORATION (JP) 1997-07-01 — — US disclosed
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