SCHEMBL4956416

SCHEMBL4956416

N#CC1=C(C#N)C(=O)c2c(Nc3ccccc3)ccc(N)c2C1=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 7/20 0.50
▸ KDM4E B2RXH2 6/20 0.50
▸ ALDH1A1 P00352 6/20 0.50
▸ MAPT P10636 7/20 0.48
▸ MEN1 O00255 5/20 0.48
▸ KMT2A Q03164 5/20 0.48
▸ HTT P42858 3/20 0.48
▸ LMNA P02545 2/20 0.48
▸ HPGD P15428 2/20 0.48
▸ SMN1; SMN2 Q16637 1/20 0.48
▸ CYP1A2 P05177 1/20 0.42
▸ CYP2D6 P10635 1/20 0.42
▸ CYP2C9 P11712 1/20 0.42
▸ CYP2C19 P33261 1/20 0.42
▸ MMP14 P50281 1/20 0.42
▸ GFER P55789 2/20 0.41
▸ THRB P10828 2/20 0.40
▸ HSD17B10 Q99714 1/20 0.40
▸ FGR P09769 1/20 0.40
▸ PIM1 P11309 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11604108 0.86 THRB (0.52) GAAKDM4EALDH1A1MAPTMEN1
SCHEMBL10876607 0.86 GAA (0.43) GAAKDM4EALDH1A1MAPTMEN1
SCHEMBL8080141 0.82 ALDH3A1 (0.37) GAAKDM4EALDH1A1MAPTMEN1
SCHEMBL10874373 0.82 MAPT (0.46) GAAKDM4EALDH1A1MAPTMEN1
SCHEMBL10877705 0.82 DHODH (0.37) GAAKDM4EALDH1A1MAPTMEN1
SCHEMBL30918998 0.81 ADORA2A (0.63) GAAKDM4EALDH1A1MAPTMEN1
SCHEMBL29527792 0.81 ADORA2A (0.63) GAAKDM4EALDH1A1MAPTMEN1
SCHEMBL169365 0.81 ADORA2A (0.63) GAAKDM4EALDH1A1MAPTMEN1
SCHEMBL5870790 0.79 CTDSP1 (0.46) GAAKDM4EALDH1A1MAPTMEN1
SCHEMBL10875079 0.79 EGFR (0.44) GAAKDM4EALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1944332-B1 Method of modifying surface layer of molded resin NAT INST OF ADVANCED IND SCIEN (JP) 2012-08-08 — — EP disclosed
EP-1944332-A2 Modification method of surface layer of molded resin article, and modification apparatus of surface layer of molded resin article National Institute of Advanced Industrial Science and Technology (JP) 2008-07-16 — — EP disclosed
US-20060156986-A1 Modification method of surface layer of molded resin article, and modification apparatus of surface layer of molded resin article NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2006-07-20 — — US disclosed
US-7078072-B1 Method of modifying surface layer of molded resin and apparatus for modifying surface layer of molded resin NATIONAL INSTITUE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2006-07-18 — — US disclosed
US-7041332-B2 Modification method of surface layer of molded resin article, and modification apparatus of surface layer of molded resin article NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2006-05-09 — — US disclosed
US-20040195206-A1 Modification method of surface layer of molded resin article, and modification apparatus of surface layer of molded resin article NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2004-10-07 — — US disclosed
EP-1179558-A1 METHOD OF MODIFYING SURFACE LAYER OF MOLDED RESIN AND APPARATUS FOR MODIFYING SURFACE LAYER OF MOLDED RESIN Japan as represented by Secretary of Agency of Industrial Science and Technology (JP) 2002-02-13 — — EP disclosed
US-6136719-A Method and arrangement for fabricating a semiconductor device LSI LOGIC CORPORATION (US) 2000-10-24 — — US disclosed
US-5643700-A Photoresist composition and method of exposing photoresist SONY CORPORATION (JP) 1997-07-01 — — US disclosed
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