Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8074035 | 0.93 | LTB4R (0.75) | LTB4R | |
| SCHEMBL8078837 | 0.91 | LTB4R (1.00) | LTB4R | |
| SCHEMBL8078502 | 0.90 | LTB4R (1.00) | LTB4R | |
| SCHEMBL9545799 | 0.89 | LTB4R (0.70) | LTB4RFFAR1 | |
| SCHEMBL9545804 | 0.89 | LTB4R (0.70) | LTB4RFFAR1 | |
| SCHEMBL8862108 | 0.89 | LTB4R (0.70) | LTB4RFFAR1 | |
| SCHEMBL8862059 | 0.84 | LTB4R (0.82) | LTB4R | |
| SCHEMBL7026815 | 0.84 | LTB4R (0.71) | LTB4R | |
| SCHEMBL9545867 | 0.82 | LTB4R (0.60) | LTB4RFFAR1 | |
| SCHEMBL8734195 | 0.81 | LTB4R (0.85) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5656636-A | TREATING PSORIASIS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-08-12 | — | — | US | claimed |
| EP-0812194-B1 | Use of substituted pyridine compounds for treating atopic dermatitis and contact dermatitis | SMITHKLINE BEECHAM CORP (US) | 2000-08-16 | — | — | EP | disclosed |
| EP-0812194-A4 | METHOD FOR TREATING ATOPIC DERMATITIS AND CONTACT DERMATITIS | SMITHKLINE BEECHAM CORP (US) | 1998-03-11 | — | — | EP | disclosed |
| EP-0812194-A1 | METHOD FOR TREATING ATOPIC DERMATITIS AND CONTACT DERMATITIS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-17 | — | — | EP | disclosed |
| US-5633258-A | Pyridine compounds for treating leukotriene-related diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-27 | — | — | US | disclosed |
| US-5631262-A | Pyridine compounds for treating leukotriene-related diseases | SMITHKLINE BEECHAM CORPORATION (US) | 1997-05-20 | — | — | US | disclosed |
| WO-1996026725-A1 | METHOD FOR TREATING ATOPIC DERMATITIS AND CONTACT DERMATITIS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-09-06 | — | — | WO | disclosed |
| EP-0604529-A1 | PYRIDINE COMPOUNDS FOR TREATING LEUKOTRIENE-RELATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1994-07-06 | — | — | EP | disclosed |
| WO-1993006085-A1 | PYRIDINE COMPOUNDS FOR TREATING LEUKOTRIENE-RELATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-04-01 | — | — | WO | disclosed |