Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 13/20 | 0.70 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.55 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9545799 | 0.96 | LTB4R (0.70) | LTB4RFFAR1CYSLTR2CYSLTR1S1PR1 | |
| SCHEMBL9545824 | 0.91 | LTB4R (0.81) | LTB4R | |
| SCHEMBL8080164 | 0.89 | LTB4R (0.84) | LTB4RFFAR1 | |
| SCHEMBL9545867 | 0.88 | LTB4R (0.60) | LTB4RFFAR1 | |
| SCHEMBL8862108 | 0.87 | LTB4R (0.70) | LTB4RFFAR1 | |
| SCHEMBL8862080 | 0.83 | LTB4R (0.61) | LTB4RCYSLTR2CYSLTR1 | |
| SCHEMBL8078837 | 0.83 | LTB4R (1.00) | LTB4R | |
| SCHEMBL7026815 | 0.82 | LTB4R (0.71) | LTB4R | |
| SCHEMBL8078502 | 0.82 | LTB4R (1.00) | LTB4R | |
| SCHEMBL8074035 | 0.82 | LTB4R (0.75) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993022285-A1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-11-11 | — | — | WO | claimed |
| WO-1993022285-A1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-11-11 | — | — | WO | disclosed |