Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 14/20 | 0.60 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.44 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.44 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.44 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9545799 | 0.92 | LTB4R (0.70) | LTB4RFFAR1 | |
| SCHEMBL9545804 | 0.88 | LTB4R (0.70) | LTB4RFFAR1 | |
| SCHEMBL8080164 | 0.82 | LTB4R (0.84) | LTB4RFFAR1 | |
| SCHEMBL8862108 | 0.80 | LTB4R (0.70) | LTB4RFFAR1 | |
| SCHEMBL9545824 | 0.79 | LTB4R (0.81) | LTB4R | |
| SCHEMBL8825251 | 0.79 | LTB4R (0.53) | LTB4RFFAR1 | |
| SCHEMBL8825256 | 0.79 | LTB4R (0.53) | LTB4RFFAR1 | |
| SCHEMBL8862080 | 0.78 | LTB4R (0.61) | LTB4R | |
| SCHEMBL8825642 | 0.77 | LTB4R (0.47) | LTB4R | |
| SCHEMBL8825645 | 0.77 | LTB4R (0.47) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993022285-A1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-11-11 | — | — | WO | disclosed |