Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ticolubant SCHEMBL29370595 | 0.83 | LTB4R (1.00) | LTB4R | |
| Ticolubant SCHEMBL1230392 | 0.83 | LTB4R (1.00) | LTB4R | |
| Ticolubant SCHEMBL1892766 | 0.83 | LTB4R (1.00) | LTB4R | |
| SCHEMBL8075075 | 0.83 | LTB4R (0.72) | LTB4R | |
| SCHEMBL6760513 | 0.82 | LTB4R (0.82) | LTB4R | |
| SCHEMBL6760517 | 0.82 | LTB4R (0.82) | LTB4R | |
| SCHEMBL8740537 | 0.81 | LTB4R (0.52) | LTB4R | |
| SCHEMBL8740539 | 0.81 | LTB4R (0.52) | LTB4R | |
| SCHEMBL8076049 | 0.80 | LTB4R (0.46) | LTB4R | |
| SCHEMBL7019212 | 0.80 | LTB4R (0.67) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733044-A4 | COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1997-03-05 | — | — | EP | claimed |
| EP-0733044-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-09-25 | — | — | EP | claimed |
| WO-1995015950-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-06-15 | — | — | WO | claimed |
| EP-0812194-B1 | Use of substituted pyridine compounds for treating atopic dermatitis and contact dermatitis | SMITHKLINE BEECHAM CORP (US) | 2000-08-16 | — | — | EP | disclosed |
| US-5990314-A | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-23 | — | — | US | disclosed |
| EP-0812194-A4 | METHOD FOR TREATING ATOPIC DERMATITIS AND CONTACT DERMATITIS | SMITHKLINE BEECHAM CORP (US) | 1998-03-11 | — | — | EP | disclosed |
| EP-0812194-A1 | METHOD FOR TREATING ATOPIC DERMATITIS AND CONTACT DERMATITIS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-17 | — | — | EP | disclosed |
| EP-0733044-A4 | COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1997-03-05 | — | — | EP | disclosed |
| EP-0733044-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-09-25 | — | — | EP | disclosed |
| WO-1996026725-A1 | METHOD FOR TREATING ATOPIC DERMATITIS AND CONTACT DERMATITIS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-09-06 | — | — | WO | disclosed |
| WO-1995015950-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1995-06-15 | — | — | WO | disclosed |