Ticolubant

Ticolubant

SCHEMBL29370595

O=C(O)/C=C/c1nc(CSc2c(Cl)cccc2Cl)ccc1OCCc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ticolubant SCHEMBL1892766 1.00 LTB4R (1.00) LTB4R
Ticolubant SCHEMBL1230392 1.00 LTB4R (1.00) LTB4R
SCHEMBL7020052 0.95 LTB4R (1.00) LTB4R
SCHEMBL7020057 0.95 LTB4R (1.00) LTB4R
SCHEMBL7016952 0.94 LTB4R (1.00) LTB4R
SCHEMBL7020389 0.94 LTB4R (1.00) LTB4R
SCHEMBL7021487 0.94 LTB4R (0.94) LTB4R
SCHEMBL7021492 0.94 LTB4R (0.94) LTB4R
SCHEMBL7020038 0.93 LTB4R (1.00) LTB4R
SCHEMBL7020046 0.93 LTB4R (1.00) LTB4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304723-A1 MODIFIED FC PROTEINS COMPRISING SITE-SPECIFIC NON-NATURAL AMINO ACID RESIDUES, CONJUGATES OF THE SAME, METHODS OF THEIR PREPARATION AND METHODS OF THEIR USE SUTRO BIOPHARMA, INC. 2025-10-02 US disclosed
US-20250236674-A9 ANTI-CD74 ANTIBODY CONJUGATES, COMPOSITIONS COMPRISING ANTI CD74 ANTIBODY CONJUGATES AND METHODS OF USING ANTI-CD74 ANTIBODY CONJUGATES SUTRO BIOPHARMA INC (US) 2025-07-24 US disclosed
US-20250236594-A1 MODIFIED AMINO ACIDS SUTRO BIOPHARMA, INC. 2025-07-24 US disclosed
CN-119954759-A Benzopyran COX-2 inhibitor and application thereof 安炎达医药技术(广州)有限公司 2025-05-09 CN disclosed
US-20250127793-A1 CONJUGATES OF SURROGATE LIGHT CHAIN CONSTRUCTS REVOPSIS HOLDINGS, LLC 2025-04-24 US disclosed
US-12269801-B2 Modified amino acids SUTRO BIOPHARMA, INC. (US) 2025-04-08 US disclosed
US-20250090676-A1 ANTI-FOLATE RECEPTOR ALPHA ANTIBODY CONJUGATES AND THEIR USES SUTRO BIOPHARMA, INC. 2025-03-20 US disclosed
US-12252552-B2 Modified Fc proteins comprising site-specific non-natural amino acid residues, conjugates of the same, methods of their preparation and methods of their use SUTRO BIOPHARMA, INC. (US) 2025-03-18 US disclosed
US-20250002595-A1 Anti-CD70 Antibody Drug Conjugates AMBRX INC (US) 2025-01-02 US disclosed
CN-111499684-B Anti-CD 70 antibody drug conjugates AMBRX公司 2024-10-22 CN disclosed
CN-109069664-B anti-CD 74 antibody conjugates, compositions comprising anti-CD 74 antibody conjugates, and methods of use of anti-CD 74 antibody conjugates 苏特罗生物制药公司 2022-05-13 CN disclosed
US-20220143209-A1 BETA-GLUCURONIDE-LINKER DRUG CONJUGATES SEAGEN INC (US) 2022-05-12 US disclosed
US-20220089759-A1 USE OF ANTI-CD40 ANTIBODIES FOR TREATMENT OF INFLAMMATORY CONDITIONS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2022-03-24 US disclosed
WO-2022061061-A1 USE OF ANTI-CD40 ANTIBODIES FOR TREATMENT OF INFLAMMATORY CONDITIONS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2022-03-24 WO disclosed
EP-3962951-A1 ANTI-BCMA ANTIBODY CONJUGATES Sutro Biopharma, Inc. (US) 2022-03-09 EP disclosed
US-20220047716-A1 COMBINATION THERAPIES WITH ANTI-FOLATE RECEPTOR ANTIBODY CONJUGATES SUTRO BIOPHARMA, INC. 2022-02-17 US disclosed
EP-3584255-B1 MODIFIED AMINO ACIDS COMPRISING AN AZIDO GROUP SUTRO BIOPHARMA INC (US) 2022-02-16 EP disclosed
EP-2099823-B2 VARIANT TARGET BINDING AGENTS AND USES THEREOF SEAGEN INC (US) 2022-02-09 EP disclosed
US-11242394-B2 Anti-CD40 antibodies BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2022-02-08 US disclosed
EP-2609932-B1 VARIANT TARGET BINDING AGENTS AND USES THEREOF SEAGEN INC (US) 2022-02-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12252552-B2 Modified Fc proteins comprising site-specific non-natural amino acid residues, conjugates of the same, methods of their preparation and methods of their use FCGR2A, FCGR3B, FCGR1A LTB4R 2559/4885
US-20250090676-A1 ANTI-FOLATE RECEPTOR ALPHA ANTIBODY CONJUGATES AND THEIR USES FOLR1, FOLR2, DHFR LTB4R 1331/4885
US-20250304723-A1 MODIFIED FC PROTEINS COMPRISING SITE-SPECIFIC NON-NATURAL AMINO ACID RESIDUES, CONJUGATES OF THE SAME, METHODS OF THEIR PREPARATION AND METHODS OF THEIR USE FCGR2A, FCGR3B, FCGR1A LTB4R 2559/4885
US-12269801-B2 Modified amino acids PTMS, DNPEP, ANPEP LTB4R 2470/4885
US-20220047716-A1 COMBINATION THERAPIES WITH ANTI-FOLATE RECEPTOR ANTIBODY CONJUGATES FOLR1, FOLR2, DHFR LTB4R 1090/4885
US-20220143209-A1 BETA-GLUCURONIDE-LINKER DRUG CONJUGATES UGT2B7, UGT1A1, UGT2B17 LTB4R 1563/4885
US-20250236594-A1 MODIFIED AMINO ACIDS PTMS, DNPEP, ANPEP LTB4R 2470/4885
US-20250236674-A9 ANTI-CD74 ANTIBODY CONJUGATES, COMPOSITIONS COMPRISING ANTI CD74 ANTIBODY CONJUGATES AND METHODS OF USING ANTI-CD74 ANTIBODY CONJUGATES CD74, CD63, CD99 LTB4R 3875/4885
US-20250002595-A1 Anti-CD70 Antibody Drug Conjugates CD63, CD74, CD99 LTB4R 3188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.