Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42660 | 0.80 | MEN1 (0.38) | DGAT1 | |
| SCHEMBL375029 | 0.75 | HCAR2 (0.45) | DGAT1ELANE | |
| SCHEMBL5898802 | 0.75 | DGAT1 (0.40) | DGAT1ELANE | |
| SCHEMBL43764 | 0.75 | HCAR2 (0.45) | DGAT1ELANE | |
| SCHEMBL43004 | 0.75 | HCAR2 (0.45) | DGAT1ELANE | |
| SCHEMBL297178 | 0.72 | — | — | |
| SCHEMBL1913508 | 0.72 | — | — | |
| SCHEMBL30658 | 0.70 | — | — | |
| Water SCHEMBL9467349 | 0.70 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL3690271 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143749-A | Heterocyclic substituted cyclopentane compounds | ABBOTT LABORATORIES (US) | 2000-11-07 | — | — | US | claimed |
| EP-0873340-A1 | HETEROCYCLIC SUBSTITUTED CYCLOPENTANE COMPOUNDS | Abbott Laboratories (US) | 1998-10-28 | — | — | EP | claimed |
| WO-1996040686-A1 | HETEROCYCLIC SUBSTITUTED CYCLOPENTANE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-19 | — | — | WO | claimed |
| US-6143749-A | Heterocyclic substituted cyclopentane compounds | ABBOTT LABORATORIES (US) | 2000-11-07 | — | — | US | disclosed |
| EP-0873340-A1 | HETEROCYCLIC SUBSTITUTED CYCLOPENTANE COMPOUNDS | Abbott Laboratories (US) | 1998-10-28 | — | — | EP | disclosed |
| WO-1996040686-A1 | HETEROCYCLIC SUBSTITUTED CYCLOPENTANE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-19 | — | — | WO | disclosed |