Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 7/20 | 0.64 |
| ▸ | LMNA | P02545 | 7/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.64 |
| ▸ | TSHR | P16473 | 4/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.64 |
| ▸ | PGR | P06401 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.64 |
| ▸ | AR | P10275 | 2/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | ESR1 | P03372 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | HTR2B | P41595 | 1/20 | 0.64 |
| ▸ | SERPINA6 | P08185 | 6/20 | 0.60 |
| ▸ | BLM | P54132 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9220296 | 0.91 | SHBG (0.66) | SHBGLMNASMN1; SMN2NR3C1TSHR | |
| SCHEMBL8080872 | 0.90 | SHBG (0.64) | SHBGLMNASMN1; SMN2NR3C1TSHR | |
| SCHEMBL9542555 | 0.86 | SHBG (0.68) | SHBGLMNASMN1; SMN2NR3C1TSHR | |
| SCHEMBL9542548 | 0.86 | SHBG (0.68) | SHBGLMNASMN1; SMN2NR3C1TSHR | |
| SCHEMBL571189 | 0.84 | SHBG (0.74) | SHBGLMNASMN1; SMN2NR3C1TSHR | |
| SCHEMBL3946610 | 0.84 | SHBG (0.74) | SHBGLMNASMN1; SMN2NR3C1TSHR | |
| SCHEMBL634733 | 0.84 | SHBG (0.74) | SHBGLMNASMN1; SMN2NR3C1TSHR | |
| SCHEMBL8077892 | 0.82 | SHBG (0.65) | SHBGLMNASMN1; SMN2NR3C1TSHR | |
| SCHEMBL11525718 | 0.82 | SHBG (0.68) | SHBGLMNASMN1; SMN2NR3C1TSHR | |
| SCHEMBL9309932 | 0.82 | SHBG (0.68) | SHBGLMNASMN1; SMN2NR3C1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028731-A2 | STABLE ANTIANDROGENIC GEL COMPOSITION | SCHERING CORPORATION (US) | 2000-08-23 | — | — | EP | disclosed |
| WO-1999024042-A2 | STABLE ANTIANDROGENIC GEL COMPOSITION | SCHERING CORPORATION (US) | 1999-05-20 | — | — | WO | disclosed |
| US-5879711-A | MIXTURE CONTAINING ANTIANDROGEN AGENT, ALCOHOL-WATER SOLVENT SYSTEM AND GELLING AGENT; ACIDIC PH | SCHERING CORPORATION | 1999-03-09 | — | — | US | disclosed |