Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4892687 | 0.70 | CYP1A2 (0.38) | ALDH1A1TSHRTGM2TDP1HSD17B10 | |
| SCHEMBL30814267 | 0.69 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1HSD17B10CTSD | |
| SCHEMBL17409617 | 0.69 | ALDH1A1 (0.50) | ALDH1A1TSHRTDP1HSD17B10CTSD | |
| SCHEMBL897646 | 0.65 | ADH1B (0.43) | ALDH1A1TDP1ALOX12IDO1CYP3A4 | |
| Biphenyl SCHEMBL11692531 | 0.65 | ALDH1A1 (0.53) | ALDH1A1TSHRTDP1HSD17B10MAPK1 | |
| SCHEMBL304279 | 0.65 | — | — | |
| SCHEMBL17046019 | 0.65 | — | — | |
| Diphenylamine SCHEMBL8598836 | 0.65 | HSD17B10 (0.71) | ALDH1A1TSHRTGM2TDP1HSD17B10 | |
| SCHEMBL13551147 | 0.65 | — | — | |
| Diphenylamine SCHEMBL2427538 | 0.65 | ALDH1A1 (0.70) | ALDH1A1TSHRTGM2TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725113-B1 | Fluorinated amide silicone compounds and curable siloxane compositions | SHINETSU CHEMICAL CO (JP) | 2000-09-27 | — | — | EP | disclosed |
| US-5665846-A | SOLVENT AND CHEMICAL RESISTANCE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0725113-A1 | Fluorinated amide silicone compounds and curable siloxane compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-08-07 | — | — | EP | disclosed |