SCHEMBL808059

SCHEMBL808059

Cc1ccc2c(c1)C1(c3cc(C)ccc3-2)c2cc(C)ccc2-c2ccc(N3c4ccccc4C(C)(C)c4ccccc43)cc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 7/20 0.40
PDK2 Q15119 4/20 0.40
NPSR1 Q6W5P4 2/20 0.34
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
KMT2A Q03164 2/20 0.33
HSD17B10 Q99714 1/20 0.33
CASP3 P42574 1/20 0.33
RAB9A P51151 1/20 0.33
ATM Q13315 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
LMNA P02545 2/20 0.32
TP53 P04637 1/20 0.32
MDM2 Q00987 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15183634 0.97 PGR (0.42) PGRPDK2NPSR1KDM4EALDH1A1
SCHEMBL12325036 0.95 PGR (0.40) PGRPDK2NPSR1KDM4EKMT2A
SCHEMBL13231559 0.91 PGR (0.37) PGRPDK2NPSR1KMT2ACYP1A2
SCHEMBL808005 0.91 PGR (0.37) PGRPDK2NPSR1KMT2ACYP1A2
SCHEMBL10134366 0.91 PGR (0.37) PGRPDK2NPSR1KMT2ACYP1A2
SCHEMBL19987417 0.88 PDK2 (0.36) PGRPDK2NPSR1KDM4EALDH1A1
SCHEMBL23331476 0.88 KMT2A (0.38) PGRPDK2NPSR1KMT2ACYP1A2
SCHEMBL15183660 0.87 PDK2 (0.38) PGRPDK2NPSR1KDM4EALDH1A1
SCHEMBL15183658 0.87 ALDH1A1 (0.43) PGRPDK2NPSR1KDM4EALDH1A1
SCHEMBL10039054 0.86 PDK2 (0.41) PGRPDK2NPSR1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2826079-B1 ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2021-01-20 EP disclosed
US-10454040-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2019-10-22 US disclosed
US-10270052-B2 Electronic device MERCK PATENT GMBH (DE) 2019-04-23 US disclosed
EP-3460864-A1 ELECTRONIC DEVICES Merck Patent GmbH (DE) 2019-03-27 EP disclosed
US-20180138439-A1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2018-05-17 US disclosed
US-20180138439-A1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2018-05-17 US disclosed
US-9947874-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2018-04-17 US disclosed
US-9947874-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2018-04-17 US disclosed
EP-2907173-B1 ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2018-03-21 EP disclosed
US-9917272-B2 Electronic device MERCK PATENT GMBH (DE) 2018-03-13 US disclosed
US-20150236261-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-08-20 US disclosed
US-20150236261-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-08-20 US disclosed
US-20150115239-A1 ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-04-30 US disclosed
US-20150115239-A1 ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-04-30 US disclosed
EP-2616428-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2014-12-24 EP disclosed
WO-2014044344-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2014-03-27 WO disclosed
WO-2013135352-A1 ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2013-09-19 WO disclosed
US-20130207046-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2013-08-15 US disclosed
US-20130207046-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2013-08-15 US disclosed
WO-2012034627-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-03-22 WO disclosed