Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 3/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13970253 | 0.83 | SLC6A9 (0.40) | CTSKCTSSCCR5ATM | |
| SCHEMBL8080629 | 0.83 | SLC6A9 (0.40) | CTSKCTSSCCR5ATM | |
| SCHEMBL13970169 | 0.83 | SLC6A9 (0.40) | CTSKCTSSCCR5ATM | |
| SCHEMBL13949277 | 0.83 | SLC6A9 (0.45) | MAPTCTSKCTSS | |
| SCHEMBL8098119 | 0.78 | OPRD1 (0.34) | CYP3A4TSHRLMNA | |
| SCHEMBL8091606 | 0.78 | OPRD1 (0.34) | CYP3A4TSHRLMNA | |
| SCHEMBL7899357 | 0.75 | MAPT (0.43) | MAPTCTSKCTSSALDH1A1 | |
| SCHEMBL8080729 | 0.74 | OPRD1 (0.41) | CYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL28264427 | 0.71 | MAPT (0.48) | MAPTCTSKCTSSCCR5ATM | |
| SCHEMBL7894745 | 0.69 | SLC6A9 (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009013535-A1 | 2-AZABICYCLO(2.2.2)OCTANE DERIVATIVES AS MODULATORS OF THE GLYCINE TRANSPORTER I RECEPTOR | ASTRAZENECA AB (SE) | 2009-01-29 | — | — | WO | disclosed |