Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | BCR | P11274 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8080886 | 0.88 | AKT1 (0.52) | ABL1MAPTSMN1; SMN2STAT3BCR | |
| SCHEMBL4250462 | 0.87 | MAPT (0.67) | ABL1MAPTSMN1; SMN2STAT3BCR | |
| SCHEMBL13663056 | 0.78 | EPHX2 (0.72) | EPHX2 | |
| SCHEMBL28000086 | 0.77 | LMNA (0.67) | ABL1MAPTSMN1; SMN2STAT3EPHX2 | |
| SCHEMBL4251642 | 0.76 | MAPT (0.62) | ABL1MAPTSMN1; SMN2STAT3EPHX2 | |
| SCHEMBL8086591 | 0.74 | CNR2 (0.56) | MAPTSMN1; SMN2ALDH1A1LMNAKCNQ3 | |
| SCHEMBL15391445 | 0.71 | ABL1 (0.70) | ABL1 | |
| SCHEMBL5863308 | 0.71 | EPHX2 (0.72) | MAPTSMN1; SMN2EPHX2GAAALDH1A1 | |
| SCHEMBL4737529 | 0.71 | KCNQ3 (0.73) | MAPTSMN1; SMN2STAT3ALDH1A1LMNA | |
| SCHEMBL5863233 | 0.70 | HDAC8 (0.62) | ABL1MAPTSMN1; SMN2EPHX2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016088-A1 | THE USE OF BENZAMIDE DERIVATIVES FOR THE TREATMENT OF CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-02-05 | — | — | WO | disclosed |