Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.56 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.48 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8081787 | 0.90 | CNR1 (0.48) | CNR2DGAT1MAPTLMNAHTT | |
| SCHEMBL4247530 | 0.87 | MAPT (0.69) | CNR2DGAT1MAPTLMNAHTT | |
| SCHEMBL8080886 | 0.81 | AKT1 (0.52) | DGAT1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL8086323 | 0.76 | KDM4E (0.54) | LMNASMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL4252309 | 0.76 | P4HTM (0.61) | DGAT1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL4250152 | 0.76 | MAPT (0.73) | DGAT1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL4249417 | 0.76 | P4HTM (0.61) | DGAT1MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL13930597 | 0.75 | P4HTM (0.60) | CNR2MAPTLMNAHTTSMN1; SMN2 | |
| SCHEMBL8080882 | 0.74 | ABL1 (0.53) | MAPTLMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL3679282 | 0.73 | P4HTM (0.58) | DGAT1MAPTLMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016088-A1 | THE USE OF BENZAMIDE DERIVATIVES FOR THE TREATMENT OF CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-02-05 | — | — | WO | disclosed |