Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.54 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.54 |
| ▸ | MME | P08473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6534842 | 0.92 | AGTR1 (0.63) | AGTR1AGTR2MME | |
| SCHEMBL6534661 | 0.90 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL9558470 | 0.84 | AGTR1 (0.52) | AGTR1AGTR2MME | |
| SCHEMBL74 | 0.82 | AGTR1 (0.74) | AGTR1AGTR2MME | |
| SCHEMBL7367303 | 0.81 | AGTR1 (0.63) | AGTR1AGTR2MME | |
| SCHEMBL6534771 | 0.80 | AGTR1 (0.75) | AGTR1AGTR2 | |
| SCHEMBL465 | 0.79 | AGTR1 (0.78) | AGTR1AGTR2MME | |
| SCHEMBL7311400 | 0.77 | AGTR1 (0.71) | AGTR1AGTR2 | |
| SCHEMBL516 | 0.76 | AGTR1 (0.75) | AGTR1AGTR2MME | |
| SCHEMBL7322206 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000508347-A | — | — | 2000-07-04 | — | — | JP | claimed |
| EP-0966282-A1 | USE OF ANGIOTENSIN II ANTAGONISTS TO TREAT SYMPTOMATIC HEART FAILURE | Merck & Co., Inc. (US) | 1999-12-29 | — | — | EP | claimed |
| WO-1998030216-A1 | USE OF ANGIOTENSIN II ANTAGONISTS TO TREAT SYMPTOMATIC HEART FAILURE | MERCK & CO., INC. (US) | 1998-07-16 | — | — | WO | claimed |
| EP-0966282-A1 | USE OF ANGIOTENSIN II ANTAGONISTS TO TREAT SYMPTOMATIC HEART FAILURE | Merck & Co., Inc. (US) | 1999-12-29 | — | — | EP | disclosed |
| WO-1998030216-A1 | USE OF ANGIOTENSIN II ANTAGONISTS TO TREAT SYMPTOMATIC HEART FAILURE | MERCK & CO., INC. (US) | 1998-07-16 | — | — | WO | disclosed |