Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 9/20 | 0.63 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.63 |
| ▸ | MME | P08473 | 8/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL74 | 0.92 | AGTR1 (0.74) | AGTR1AGTR2MME | |
| SCHEMBL465 | 0.89 | AGTR1 (0.78) | AGTR1AGTR2MME | |
| SCHEMBL516 | 0.86 | AGTR1 (0.75) | AGTR1AGTR2MME | |
| SCHEMBL33 | 0.85 | AGTR1 (0.75) | AGTR1AGTR2 | |
| SCHEMBL6545454 | 0.84 | AGTR1 (0.63) | AGTR1AGTR2MME | |
| SCHEMBL6534842 | 0.82 | AGTR1 (0.63) | AGTR1AGTR2MME | |
| SCHEMBL10589740 | 0.82 | AGTR1 (0.66) | AGTR1AGTR2MME | |
| SCHEMBL359 | 0.81 | GP6 (0.63) | AGTR1AGTR2 | |
| SCHEMBL8080987 | 0.81 | AGTR1 (0.54) | AGTR1AGTR2MME | |
| SCHEMBL3658233 | 0.80 | GP6 (0.61) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992000067-A2 | TREATMENT OF CHRONIC RENAL FAILURE WITH IMIDAZOLE ANGIOTENSIN-II RECEPTOR ANTAGONISTS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-01-09 | — | — | WO | disclosed |