Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL830413 | 0.83 | ALDH1A1 (0.44) | KMOALDH1A1L3MBTL1AKR1B10AKR1C4 | |
| SCHEMBL830823 | 0.82 | KMO (0.43) | KMOALDH1A1L3MBTL1AKR1B10AKR1C4 | |
| SCHEMBL831823 | 0.82 | KMO (0.42) | KMOALDH1A1L3MBTL1AKR1B10AKR1C4 | |
| SCHEMBL831371 | 0.80 | KMO (0.45) | KMOALDH1A1L3MBTL1AKR1B10AKR1C4 | |
| SCHEMBL831344 | 0.79 | KMO (0.44) | KMOALDH1A1L3MBTL1AKR1B10AKR1C4 | |
| SCHEMBL831342 | 0.79 | KMO (0.44) | KMOALDH1A1L3MBTL1AKR1B10AKR1C4 | |
| SCHEMBL831459 | 0.74 | KMO (0.43) | KMOALDH1A1L3MBTL1AKR1B10AKR1C4 | |
| SCHEMBL839778 | 0.74 | VCP (0.43) | KMOALDH1A1L3MBTL1AKR1B10AKR1C4 | |
| SCHEMBL829626 | 0.74 | ALDH1A1 (0.50) | KMOALDH1A1L3MBTL1AKR1B10AKR1C4 | |
| SCHEMBL831457 | 0.74 | ALDH1A1 (0.46) | KMOALDH1A1L3MBTL1AKR1B10AKR1C4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009033561-A1 | SUBSTITUTED 6-PHEYLNICOTINIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-03-19 | — | — | WO | disclosed |