Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8081340 | 0.87 | POLB (0.44) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL8081350 | 0.87 | POLB (0.44) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL8082178 | 0.86 | LMNA (0.44) | MAPTLMNAMAPK1L3MBTL1NPC1 | |
| SCHEMBL8082109 | 0.84 | NPC1 (0.59) | MAPTLMNANPC1RAB9ANPSR1 | |
| SCHEMBL20591945 | 0.73 | MAPT (0.47) | MAPTLMNAMAPK1L3MBTL1NPSR1 | |
| SCHEMBL2257606 | 0.72 | LMNA (0.56) | LMNAMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL8087323 | 0.70 | NPC1 (0.64) | LMNANPC1RAB9AMEN1KMT2A | |
| SCHEMBL2255527 | 0.70 | MEN1 (0.52) | LMNAMEN1KMT2AHTTRAD52 | |
| SCHEMBL3455798 | 0.69 | NPC1 (0.59) | LMNANPC1RAB9AMEN1KMT2A | |
| SCHEMBL2255114 | 0.69 | HIF1A (0.48) | LMNAMEN1KMT2AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702689-B1 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR 3-PHENYL-1-ADAMANTANEACETIC ACIDS | ABBOTT LAB (US) | 2000-10-11 | — | — | EP | disclosed |
| EP-0702689-A4 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR 3-PHENYL-1-ADAMANTANEACETIC ACIDS | ABBOTT LAB (US) | 1997-10-22 | — | — | EP | disclosed |
| US-5616505-A | Haptens tracers, immunogens and antibodies for 3-phenyl-1-adamantaneacetic acids | ABBOTT LABORATORIES (US) | 1997-04-01 | — | — | US | disclosed |
| EP-0702689-A1 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR 3-PHENYL-1-ADAMANTANEACETIC ACIDS | ABBOTT LABORATORIES (US) | 1996-03-27 | — | — | EP | disclosed |
| US-5424414-A | Haptens, tracers, immunogens and antibodies for 3-phenyl-1-adamantaneacetic acids | ABBOTT LABORATORIES (US) | 1995-06-13 | — | — | US | disclosed |
| WO-1994029329-A1 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR 3-PHENYL-1-ADAMANTANEACETIC ACIDS | ABBOTT LABORATORIES (US) | 1994-12-22 | — | — | WO | disclosed |