Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 6/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | QDPR | P09417 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | MAT2A | P31153 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 2/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12413 | 0.76 | CA1 (0.45) | HTR2CARHTR2AHTR2B | |
| SCHEMBL31158608 | 0.74 | HTR2C (0.49) | HTR2CARHTR2AHTR2B | |
| SCHEMBL13894872 | 0.74 | HTR2C (0.51) | HTR2CARHTR2AHTR2B | |
| SCHEMBL7036293 | 0.74 | CHRNB2 (0.42) | HTR2CARHTR2AHTR2B | |
| SCHEMBL21241465 | 0.72 | EPHX2 (0.39) | ESR2HTR2CQDPREPHX2PDE4A | |
| SCHEMBL12649161 | 0.71 | HTR2C (0.54) | HTR2CHTR2AHTR2BPOLB | |
| SCHEMBL12983195 | 0.71 | PARP1 (0.37) | HTR2CARHTR2AHTR2B | |
| SCHEMBL18883053 | 0.69 | HTR2C (0.46) | HTR2CARHTR2AHTR2B | |
| SCHEMBL13372443 | 0.69 | HTR2C (0.46) | HTR2CARHTR2AHTR2B | |
| SCHEMBL548964 | 0.69 | HTR2C (0.46) | HTR2CARHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009053440-A1 | INDOLINE COMPOUNDS | FERRER INTERNACIONAL S.A. (ES) | 2009-04-30 | — | — | WO | disclosed |