SCHEMBL8081801

SCHEMBL8081801

C=CCc1c(C(=O)O)cccc1C(=O)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 3/20 0.55
CDC25B P30305 2/20 0.45
ATM Q13315 2/20 0.45
POLB P06746 1/20 0.44
NR4A1 P22736 1/20 0.44
KDM4E B2RXH2 1/20 0.44
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
ALDH1A1 P00352 3/20 0.43
LMNA P02545 1/20 0.43
HPGD P15428 1/20 0.43
CDC25A P30304 1/20 0.41
HSD17B10 Q99714 1/20 0.41
ALOX15 P16050 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
SRD5A2 P31213 1/20 0.40
CYP2C8 P10632 1/20 0.40
CYP2C9 P11712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1758773 0.88 ALDH1A1 (0.46) POLBNR4A1KDM4EGAAMAPT
SCHEMBL28973887 0.86 ALDH1A1 (0.44) POLBNR4A1KDM4EGAAMAPT
SCHEMBL253177 0.86 LIG1 (0.45) AKR1C3ATMKDM4EGAAMAPT
SCHEMBL474923 0.86 AKR1C3 (0.44) AKR1C3ATMPOLBKDM4EGAA
SCHEMBL15796982 0.84 AKR1C3 (0.43) AKR1C3CDC25BATMGAAMAPT
SCHEMBL2212691 0.84 MAPT (0.57) AKR1C3POLBGAAMAPTALDH1A1
SCHEMBL8487646 0.82 AKR1C3 (0.41) AKR1C3CDC25BATMGAAMAPT
SCHEMBL30581210 0.81 ELANE (0.44) AKR1C3KDM4EGAAMAPTALDH1A1
SCHEMBL9614734 0.80 KDM4E (0.43) NR4A1KDM4EGAAMAPTALDH1A1
SCHEMBL3805424 0.79 AKR1C3 (0.49) AKR1C3CDC25BATMPOLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0735426-B1 Radiation curable polymers and method of producing the same DAINIPPON INK & CHEMICALS (JP) 2000-10-11 EP disclosed
US-5847022-A Radiation curable resin composition and method therefor DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-12-08 US disclosed
EP-0735426-A1 Radiation curable polymers and method of producing the same DAINIPPON INK AND CHEMICALS, INC. (JP) 1996-10-02 EP disclosed