SCHEMBL474923

SCHEMBL474923

C=CCc1cccc(C(=O)c2ccccc2)c1CC=C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.44
ELANE P08246 1/20 0.43
GAA P10253 2/20 0.42
MAPT P10636 1/20 0.42
ALDH1A1 P00352 2/20 0.42
LMNA P02545 1/20 0.42
HPGD P15428 1/20 0.42
GABRA1 P14867 1/20 0.41
GABRB2 P47870 1/20 0.41
TSHR P16473 1/20 0.41
KDM4E B2RXH2 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
POLB P06746 1/20 0.40
CYP19A1 P11511 1/20 0.40
MEN1 O00255 1/20 0.39
USP2 O75604 1/20 0.39
KMT2A Q03164 1/20 0.39
KEAP1 Q14145 1/20 0.39
NFE2L2 Q16236 1/20 0.39
ATM Q13315 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30581210 0.89 ELANE (0.44) AKR1C3ELANEGAAMAPTALDH1A1
SCHEMBL30560007 0.87 AKR1C3 (0.50) AKR1C3ELANEGAAMAPTALDH1A1
SCHEMBL170063 0.87 AKR1C3 (0.50) AKR1C3ELANEGAAMAPTALDH1A1
SCHEMBL943893 0.87 AKR1C3 (0.50) AKR1C3ELANEGAAMAPTALDH1A1
Benzophenone SCHEMBL28421417 0.86 ELANE (0.41) AKR1C3ELANEGAAMAPTALDH1A1
SCHEMBL8081801 0.86 AKR1C3 (0.55) AKR1C3GAAMAPTALDH1A1LMNA
Ethylene SCHEMBL11742925 0.85 AKR1C3 (0.48) AKR1C3ELANEGAAMAPTALDH1A1
Ammonia Solution, Strong SCHEMBL28897507 0.85 AKR1C3 (0.48) AKR1C3ELANEGAAMAPTALDH1A1
SCHEMBL253177 0.84 LIG1 (0.45) AKR1C3GAAMAPTALDH1A1LMNA
SCHEMBL508302 0.84 GABRA1 (0.53) AKR1C3ELANEGAAMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1739484-A2 Photosensitive lithographic printing plate and method for making a prinitng plate. LASTRA S.P.A. (IT) 2007-01-03 EP claimed
CN-116931370-A Photosensitive resin composition and cured product 新应材股份有限公司 2023-10-24 CN disclosed
CN-116931371-A Photosensitive resin composition and cured product 新应材股份有限公司 2023-10-24 CN disclosed
WO-2023281971-A1 ACTIVE-ENERGY-RAY-CURABLE RESIN COMPOSITION, ACTIVE-ENERGY-RAY-CURABLE PIGMENT DISPERSION, INK COMPOSITION FOR OFFSET INK, AND INK COMPOSITION FOR FLEXOGRAPHIC INK 東洋インキSCホールディングス株式会社 2023-01-12 WO disclosed
CN-111032102-A Polymer coatings 科洛普拉斯特公司 2020-04-17 CN disclosed
US-10470874-B2 Adjustable optical elements with enhanced ultraviolet protection RXSIGHT, INC. (US) 2019-11-12 US disclosed
US-20190262125-A9 NOVEL ADJUSTABLE OPTICAL ELEMENTS WITH ENHANCED ULTRAVIOLET PROTECTION RXSIGHT, INC. (US) 2019-08-29 US disclosed
EP-3123980-A1 ADJUSTABLE OPTICAL ELEMENTS WITH ENHANCED ULTRAVIOLET PROTECTION Calhoun Vision, Inc. (US) 2017-02-01 EP disclosed
US-20170020658-A1 NOVEL ADJUSTABLE OPTICAL ELEMENTS WITH ENHANCED ULTRAVIOLET PROTECTION Calhoun Vision, Inc, (US) 2017-01-26 US disclosed
CN-101321505-B There is the novel adjustable optical elements strengthening ultraviolet protection CALHOUN VISION, INC. (US) 2015-12-02 CN disclosed
US-20060142528-A1 Initiator and ultraviolet absorber blends for changing lens power by ultraviolet light CALHOUN VISION, INC (US) 2006-06-29 US disclosed
EP-0343467-B1 HOT MELT ADHESIVES CROSS-LINKABLE IN THE AIR, USING ULTRAVIOLET RADIATION BASF Aktiengesellschaft (DE) 1992-12-23 EP disclosed
EP-0355028-B1 METHOD FOR PREVENTING WEATHERING OF MINERAL SUBSTRATES BASF Aktiengesellschaft (DE) 1992-05-06 EP disclosed
US-5047443-A Hotmelt contact adhesives which can be crosslinked with ultraviolet radiation in the presence of oxygen BASF AKTIENGESELLSCHAFT (DE) 1991-09-10 US disclosed
EP-0441221-A1 Method for preventing the appearance of efflorescence of mineral substrates BASF Aktiengesellschaft (DE) 1991-08-14 EP disclosed
US-4999218-A (Meth)acrylate copolymer and aromatic ketone dispersion; concrete roof tiles BASF AKTIENGESELLSCHAFT (DE) 1991-03-12 US disclosed
US-4912596-A Dielectric liquids BAYER AKTIENGESELLSCHAFT (DE) 1990-03-27 US disclosed
EP-0355028-A1 Method for preventing weathering of mineral substrates BASF Aktiengesellschaft (DE) 1990-02-21 EP disclosed
EP-0343467-A2 Hot melt adhesives cross-linkable in the air, using ultraviolet radiation BASF Aktiengesellschaft (DE) 1989-11-29 EP disclosed
EP-0105630-B1 PRODUCTION OF PARA-CRESOL CELGENE CORPORATION (US) 1988-08-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10470874-B2 Adjustable optical elements with enhanced ultraviolet protection UACA, ERCC4, CRYAB AKR1C3 1540/4885ELANE 2893/4885GAA 1616/4885
US-20190262125-A9 NOVEL ADJUSTABLE OPTICAL ELEMENTS WITH ENHANCED ULTRAVIOLET PROTECTION UACA, ERCC4, CRYZ AKR1C3 1566/4885ELANE 2981/4885GAA 1797/4885
US-20170020658-A1 NOVEL ADJUSTABLE OPTICAL ELEMENTS WITH ENHANCED ULTRAVIOLET PROTECTION UACA, ERCC4, CRYZ AKR1C3 1566/4885ELANE 2981/4885GAA 1797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.