SCHEMBL8081829

SCHEMBL8081829

CCCC[Ti](OC(C)C)(OC(C)C)OC(C)C

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.35
LMNA P02545 3/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19713159 0.92 OPRM1 (0.39) OPRM1LMNATSHR
SCHEMBL19713151 0.90 TSHR (0.38) OPRM1LMNATSHR
SCHEMBL19713120 0.90 TSHR (0.38) OPRM1LMNATSHR
SCHEMBL5837368 0.83
SCHEMBL8087926 0.71
SCHEMBL2049395 0.70 TSHR (0.38) OPRM1LMNATSHR
SCHEMBL1795539 0.69 TSHR (0.35) LMNATSHR
SCHEMBL129869 0.66 TSHR (0.46) LMNATSHR
SCHEMBL1361238 0.65 ADRB2 (0.35) TSHR
SCHEMBL10405702 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1043298-A1 PROCESSES FOR THE PREPARATION OF ALCOHOLS Daicel Chemical Industries, Ltd. (JP) 2000-10-11 EP disclosed
WO-1995006672-A1 IMPROVED CATALYSTS FOR POLYMERIZING OLEFINS OCCIDENTAL CHEMICAL CORPORATION (US) 1995-03-09 WO disclosed
US-4851489-A ALUMINUM-POLYETHYLENE COORDINATION CATALYST EXXON RESEARCH & ENGINEERING COMPANY (US) 1989-07-25 US disclosed
EP-0134100-B1 COCATALYST FOR USE WITH A TRANSITION METAL COMPOUND IN POLYETHYLENE PRODUCTION EXXON RESEARCH AND ENGINEERING COMPANY (US) 1989-02-15 EP disclosed
EP-0129313-B1 POLYETHYLENE WITH LONG CHAIN BRANCHING AND ZIEGLER-NATTA CATALYST FOR ITS PREPARATION EXXON RESEARCH AND ENGINEERING COMPANY (US) 1987-06-10 EP disclosed
US-4657998-A POLYMERIZATION CATALYSTS OF A TITANIUM COMPONENT, ISOPRENYLALUMINUM AND A HALOHYDROCARBON EXXON RESEARCH & ENGINEERING CO. (US) 1987-04-14 US disclosed
US-4593010-A Coordination catalyst of transition metal compound, organoaluminum compounds and a halogenated hydrocarbon EXXON RESEARCH & ENGINEERING CO. (US) 1986-06-03 US disclosed
EP-0134100-A1 Cocatalyst for use with a transition metal compound in polyethylene production EXXON RESEARCH AND ENGINEERING COMPANY (US) 1985-03-13 EP disclosed
US-4500648-A GROUP 4 TO 8 TRANSITION METAL COMPOUND, ORGANOALUMINUM COMPOUND, AND ALUMINUM ALICYL COCATALYST EXXON RESEARCH & ENGINEERING CO. (US) 1985-02-19 US disclosed
EP-0129313-A1 Polyethylene with long chain branching and Ziegler-Natta catalyst for its preparation EXXON RESEARCH AND ENGINEERING COMPANY (US) 1984-12-27 EP disclosed
US-4319011-A High efficiency, high temperature catalyst for polymerizing olefins THE DOW CHEMICAL CO. (US) 1982-03-09 US disclosed
US-4314912-A High efficiency, high temperature catalyst for polymerizing olefins THE DOW CHEMICAL COMPANY (US) 1982-02-09 US disclosed
US-4250288-A COORDINATION CATALYST COMPRISING A TRANSITION METAL COMPOUND, AN ORGANOMAGNESIUM COMPOUND OR COMPLEX, A NONMETAL HALIDE, AND AN ORGANOALUMINUM COMPOUND; NONCONTAMINATING THE DOW CHEMICAL COMPANY (US) 1981-02-10 US disclosed
US-4172050-A High efficiency titanate catalyst for polymerizing olefins THE DOW CHEMICAL COMPANY (US) 1979-10-23 US disclosed