Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.30 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20526999 | 0.79 | RAB9A (0.43) | MCL1ALDH1A1 | |
| SCHEMBL20526969 | 0.79 | ATM (0.41) | ALDH1A1GAASMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL18702981 | 0.77 | MAOA (0.53) | KDM4EALDH1A1L3MBTL1MAOAHPGD | |
| SCHEMBL21964009 | 0.76 | LOXL2 (0.39) | LOXL2PIM1PIM3KDM4EALDH1A1 | |
| SCHEMBL8038421 | 0.76 | LOXL2 (0.40) | LOXL2MCL1KDM4EALDH1A1GAA | |
| SCHEMBL2089679 | 0.76 | LOXL2 (0.40) | LOXL2MCL1KDM4EALDH1A1GAA | |
| SCHEMBL23531992 | 0.74 | CYP2A6 (0.38) | PIM1PIM3ALDH1A1L3MBTL1MAOA | |
| SCHEMBL13298377 | 0.73 | NQO1 (0.38) | LOXL2MCL1KDM4EALDH1A1GAA | |
| SCHEMBL31495900 | 0.73 | LOXL2 (0.35) | LOXL2 | |
| SCHEMBL15678569 | 0.71 | LOXL2 (0.50) | LOXL2KDM4EALDH1A1SMN1; SMN2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063810-A | ENANTIOMORPHS | SYNTHELABO (FR) | 2000-05-16 | — | — | US | disclosed |
| EP-0888324-A1 | 2-AMINOETHYL-BENZOFURAN DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USE THEREOF | SYNTHELABO (FR) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997032870-A1 | 2-AMINOETHYL-BENZOFURAN DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USE THEREOF | SYNTHELABO (FR) | 1997-09-12 | — | — | WO | disclosed |