SCHEMBL8082227

SCHEMBL8082227

CCOC(CCCNS(=O)(=O)c1ccc(NC(C)=O)cc1)OCC

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.64
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
ALDH1A1 P00352 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
CA1 P00915 3/20 0.53
CA2 P00918 3/20 0.53
CA12 O43570 1/20 0.53
CA9 Q16790 1/20 0.53
CYP1A2 P05177 1/20 0.52
CYP2D6 P10635 1/20 0.52
CYP2C19 P33261 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
LMNA P02545 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
MAPK1 P28482 1/20 0.50
MAPT P10636 1/20 0.49
RAB9A P51151 1/20 0.49
MMP1 P03956 1/20 0.49
MMP2 P08253 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4594909 0.82 POLB (0.79) POLBMEN1KMT2AALDH1A1NPSR1
SCHEMBL8079254 0.80 ALDH1A1 (0.58) ALDH1A1NPSR1LMNASMN1; SMN2MAPK1
SCHEMBL4066416 0.80 POLB (0.77) POLBMEN1KMT2AALDH1A1NPSR1
SCHEMBL9775630 0.79 POLB (0.75) POLBMEN1KMT2AALDH1A1NPSR1
SCHEMBL28079515 0.79 POLB (0.79) POLBMEN1KMT2AALDH1A1NPSR1
SCHEMBL9614881 0.79 POLB (0.84) POLBMEN1KMT2AALDH1A1NPSR1
SCHEMBL2616742 0.78 POLB (0.64) POLBMEN1KMT2AALDH1A1NPSR1
SCHEMBL12912609 0.78 POLB (0.77) POLBMEN1KMT2AALDH1A1NPSR1
SCHEMBL7160320 0.78 POLB (0.77) POLBMEN1KMT2AALDH1A1NPSR1
SCHEMBL11247690 0.78 POLB (0.68) POLBMEN1KMT2AALDH1A1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0757061-B1 Sulfonamido substituted acetal polymers and use thereof in photosensitive compositions and lithographic printing plates KODAK POLYCHROME GRAPHICS LLC (US) 2000-09-13 EP disclosed
US-5698360-A Sulfonamido substituted acetal polymers and use thereof in photo-sensitive compositions and lithographic printing plates SUN CHEMICAL CORPORATION (US) 1997-12-16 US disclosed
EP-0757061-A2 Sulfonamido substituted acetal polymers and use thereof in photosensitive compositions and lithographic printing plates SUN CHEMICAL CORPORATION (US) 1997-02-05 EP disclosed