SCHEMBL8082279

SCHEMBL8082279

Cc1ccc(S(=O)(=O)O)c(-c2ccc(-c3cc(C)ccc3S(=O)(=O)O)cc2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.41
MAOB P27338 3/20 0.41
PTGS2 P35354 3/20 0.40
ELANE P08246 1/20 0.39
SLC9A1 P19634 1/20 0.39
PTGS1 P23219 1/20 0.39
GAA P10253 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
RECQL P46063 1/20 0.38
CASP6 P55212 1/20 0.38
KMT2A Q03164 1/20 0.38
ELAVL1 Q15717 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1117961 0.98 PTGS2 (0.42) MAOAMAOBPTGS2ELANESLC9A1
SCHEMBL4908035 0.93 MAOB (0.44) MAOAMAOBGAAALDH1A1HSD17B10
SCHEMBL778954 0.91 PTGS2 (0.42) PTGS2PTGS1GAAMEN1KMT2A
SCHEMBL28728505 0.91 RAPGEF4 (0.37) MAOAMAOBPTGS2ELANESLC9A1
SCHEMBL3151094 0.91 HDAC7 (0.49) MAOBELANEGAAKDM4EMEN1
SCHEMBL5608505 0.90 TSHR (0.44) KDM4EALDH1A1MAPT
SCHEMBL10372894 0.88 ALKBH3 (0.50) MAOBPTGS2PTGS1KDM4EMEN1
SCHEMBL10484477 0.88 RXRA (0.49) SLC9A1GAAKDM4EALDH1A1POLB
SCHEMBL7755662 0.87 TDP1 (0.46) MAOAMAOBPTGS2ELANESLC9A1
SCHEMBL7936624 0.87 GRM2 (0.45) ALDH1A1CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0758013-B1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL CO LTD (JP) 2000-10-11 EP disclosed
US-5855971-A Liquid crystalline optical film, compensating film for liquid crystal display comprising the liquid crystalline optical film, and liquid crystal display having the compensating film NIPPON OIL COMPANY, LIMITED (JP) 1999-01-05 US disclosed
EP-0758013-A1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL COMPANY, LIMITED (JP) 1997-02-12 EP disclosed