Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8976663 | 0.82 | L3MBTL1 (0.47) | TDP1L3MBTL1GPR35PLAUTSHR | |
| SCHEMBL5682648 | 0.77 | GPR35 (0.67) | TDP1L3MBTL1GPR35PLAUTSHR | |
| SCHEMBL25310 | 0.75 | HSD17B10 (0.50) | TDP1L3MBTL1GPR35PLAUTSHR | |
| SCHEMBL1476531 | 0.75 | TDP1 (0.74) | TDP1L3MBTL1GPR35TSHRALDH1A1 | |
| SCHEMBL55225 | 0.74 | GPR35 (0.55) | TDP1GPR35PLAUTSHRALDH1A1 | |
| SCHEMBL3345170 | 0.74 | TDP1 (0.48) | TDP1GPR35PLAUTSHRALDH1A1 | |
| SCHEMBL10825048 | 0.73 | TDP1 (0.47) | TDP1GPR35PLAUTSHRALDH1A1 | |
| SCHEMBL5160633 | 0.73 | TDP1 (0.67) | TDP1L3MBTL1GPR35TSHRALDH1A1 | |
| SCHEMBL28273550 | 0.73 | TDP1 (0.47) | TDP1GPR35PLAUTSHRALDH1A1 | |
| SCHEMBL5222485 | 0.73 | TDP1 (0.47) | TDP1GPR35PLAUTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6159988-A | Arylcycloalkyl derivatives, their production and their use | HOESCHST AKTIENGESELLSCHAFT (DE) | 2000-12-12 | — | — | US | disclosed |
| US-5776977-A | Arylcycloalkyl derivatives, their production and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-07 | — | — | US | disclosed |
| US-5589514-A | ANTIINFLAMMATORY | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-12-31 | — | — | US | disclosed |
| EP-0551849-B1 | Novel arylcycloalkyl derivatives their production and their use | HOECHST AG (DE) | 1996-10-09 | — | — | EP | disclosed |
| EP-0551849-A1 | Novel arylcycloalkyl derivatives their production and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-21 | — | — | EP | disclosed |