SCHEMBL25310

SCHEMBL25310

O=[C]c1ccccc1[N+](=O)[O-]

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.50
PLAU P00749 1/20 0.50
TDP1 Q9NUW8 5/20 0.48
ALDH1A1 P00352 8/20 0.47
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
GPR35 Q9HC97 1/20 0.46
HPGD P15428 1/20 0.46
TSHR P16473 3/20 0.45
NPC1 O15118 1/20 0.44
RECQL P46063 1/20 0.44
RAB9A P51151 1/20 0.44
MAPK1 P28482 1/20 0.42
CASP7 P55210 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
PTPRC P08575 1/20 0.41
S100A4 P26447 1/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12286918 0.84 HSD17B10 (0.52) HSD17B10PLAUTDP1ALDH1A1KMT2A
SCHEMBL6210197 0.84 ALDH1A1 (0.55) HSD17B10PLAUTDP1ALDH1A1KMT2A
SCHEMBL55225 0.81 GPR35 (0.55) HSD17B10PLAUTDP1ALDH1A1KMT2A
SCHEMBL3345170 0.81 TDP1 (0.48) HSD17B10PLAUTDP1ALDH1A1KMT2A
SCHEMBL9149859 0.80 PLAU (0.36) HSD17B10PLAUTDP1ALDH1A1KMT2A
SCHEMBL10870335 0.80 KMT2A (0.50) HSD17B10PLAUTDP1ALDH1A1KMT2A
SCHEMBL56638 0.80 VCAM1 (0.56) HSD17B10PLAUTDP1ALDH1A1KMT2A
SCHEMBL562027 0.80 HSD17B10 (0.48) HSD17B10PLAUTDP1ALDH1A1KMT2A
SCHEMBL3754878 0.80 HSD17B10 (0.48) HSD17B10PLAUTDP1ALDH1A1KMT2A
SCHEMBL5671061 0.80 HSD17B10 (0.54) HSD17B10PLAUTDP1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4150 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115038790-B Synthesis of 3' -RNA oligonucleotides 阿尔尼拉姆医药品有限公司 2024-06-21 CN claimed
CN-118159542-A Substituted 2, 3-dihydro [1,3] thiazolo [4,5-b ] pyridines, salts thereof and their use as herbicidal agents 拜耳公司 2024-06-07 CN claimed
CN-110678447-B Modified nucleic acid monomer compounds and oligonucleotide analogues 卫材R&D管理有限公司 2023-12-12 CN claimed
CN-116947851-A 8-acylmethylene berberine derivative, and preparation method and application thereof 上海应用技术大学 2023-10-27 CN claimed
CN-113929748-B Kit for detecting BACE1 enzyme activity and application thereof 中国科学技术大学 2023-10-20 CN claimed
US-11713340-B2 Divalent nucleobase compounds and uses therefor CARNEGIE MELLON UNIVERSITY (US) 2023-08-01 US claimed
WO-2023121566-A1 PROCESS FOR PREPARING CEDAZURIDINE SCINOPHARM SINGAPORE PTE LTD. (SG) 2023-06-29 WO claimed
WO-2023064530-A1 EXTRA-HEPATIC DELIVERY IRNA COMPOSITIONS AND METHODS OF USE THEREOF ALNYLAM PHARMACEUTICALS, INC. (US) 2023-04-20 WO claimed
US-11603369-B2 Divalent nucleobase compounds and uses therefor CARNEGIE MELLON UNIVERSITY (US) 2023-03-14 US claimed
CN-110577489-B Synthetic method of narcotic analgesic 宜昌人福药业有限责任公司 2023-02-21 CN claimed
US-4053486-A STEREOSPECIFIC TOTAL STEROIDAL SYNTHESIS VIA SUBSTITUTED C/D-TRANS INDANONES HOFFMANN-LA ROCHE INC. (US) 1977-10-11 US claimed
US-4048195-A Process of synthesizing substituted indanones HOFFMANN-LA ROCHE INC. (US) 1977-09-13 US claimed
US-4022829-A INTERMEDIATES FOR SUNSCREEN AGENTS COLGATE-PALMOLIVE COMPANY (US) 1977-05-10 US claimed
US-4006163-A POLYESTERS CIBA-GEIGY CORPORATION (US) 1977-02-01 US claimed
US-3997524-A Process for the manufacture of 6'-N-alkyl derivatives of sisomicin and verdamicin; novel intermediates useful therein, and novel 6'-N-alkylverdamicins prepared thereby SCHERING CORPORATION (US) 1976-12-14 US claimed
US-3988326-A Process for N-acylation of 7 amino cephem compounds MEIJI SEIKA KAISHA, LTD. (JA) 1976-10-26 US claimed
US-3988142-A Increasing carbohydrate deposition in plants with N-phosphono-methylglycine and derivatives thereof MONSANTO COMPANY (US) 1976-10-26 US claimed
US-3985733-A Stereospecific total steroidal synthesis via substituted C/D-trans indanones HOFFMANN-LA ROCHE INC. (US) 1976-10-12 US claimed
US-3962214-A Process for preparing amino substituted β-lactam antibiotics ELI LILLY AND COMPANY (US) 1976-06-08 US claimed
US-3954731-A Process for preparing 6-alkoxypenicillanic and 7-alkoxycephalosporin acids ELI LILLY AND COMPANY (US) 1976-05-04 US claimed