Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 8/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935797 | 1.00 | PPARA (0.49) | PPARASMN1; SMN2PPARGTSHRPTPN1 | |
| Hydrochloric Acid SCHEMBL8074407 | 0.98 | PPARA (0.48) | PPARASMN1; SMN2PPARGTSHRPTPN1 | |
| SCHEMBL8083193 | 0.89 | TSHR (0.42) | PPARASMN1; SMN2PPARGTSHRMAPT | |
| SCHEMBL8082709 | 0.87 | PPARG (0.56) | PPARAPPARGTSHRLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL8074440 | 0.86 | PPARG (0.55) | PPARASMN1; SMN2PPARGTSHRLMNA | |
| SCHEMBL8074404 | 0.85 | PPARA (0.42) | PPARASMN1; SMN2PPARGTSHRMAPT | |
| SCHEMBL8074400 | 0.84 | PIN1 (0.44) | PPARATSHRLMNAKMT2ANPC1 | |
| SCHEMBL2103556 | 0.81 | PKM (0.54) | PPARASMN1; SMN2PPARGMAPTLMNA | |
| SCHEMBL8935912 | 0.81 | SMN1; SMN2 (0.49) | PPARASMN1; SMN2PPARGPTPN1 | |
| SCHEMBL8935919 | 0.81 | SMN1; SMN2 (0.49) | PPARASMN1; SMN2PPARGPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110039841-A1 | Novel compounds, their preparation and use | NOVO NORDISK A/S (DK) | 2011-02-17 | — | — | US | disclosed |
| US-7091237-B2 | Furan and thiophene derivatives that activate human peroxisome proliferator activated receptors | SMITHKLINE BEECHAM CORPORATION (US) | 2006-08-15 | — | — | US | disclosed |
| US-20040157890-A1 | Furan and thiophene derivatives that activate human peroxisome profilerator activated receptors | GLAXO GROUP LIMITED (GB) | 2004-08-12 | — | — | US | disclosed |
| US-6063810-A | ENANTIOMORPHS | SYNTHELABO (FR) | 2000-05-16 | — | — | US | disclosed |
| EP-0888324-A1 | 2-AMINOETHYL-BENZOFURAN DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USE THEREOF | SYNTHELABO (FR) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997032870-A1 | 2-AMINOETHYL-BENZOFURAN DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USE THEREOF | SYNTHELABO (FR) | 1997-09-12 | — | — | WO | disclosed |
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |
| EP-0109225-B1 | ARACHIDONIC ACID ANALOGUES, PROCESSES FOR THEIR PREPARATION AND THEIR USE IN MEDICINE | BEECHAM GROUP PLC (GB) | 1985-08-28 | — | — | EP | disclosed |
| EP-0109225-A1 | Arachidonic acid analogues, processes for their preparation and their use in medicine | BEECHAM GROUP PLC (GB) | 1984-05-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110039841-A1 | Novel compounds, their preparation and use | PPARG, PPARD, PPARA | PPARA 3/4885SMN1; SMN2 4002/4885PPARG 1/4885 |
| US-20040157890-A1 | Furan and thiophene derivatives that activate human peroxisome profilerator activated receptors | PPARG, PPARD, PPARA | PPARA 3/4885SMN1; SMN2 3688/4885PPARG 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.