Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 8/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1245341 | 1.00 | PPARA (0.49) | PPARASMN1; SMN2PPARGTSHRPTPN1 | |
| Hydrochloric Acid SCHEMBL8074407 | 0.98 | PPARA (0.48) | PPARASMN1; SMN2PPARGTSHRPTPN1 | |
| SCHEMBL8083193 | 0.89 | TSHR (0.42) | PPARASMN1; SMN2PPARGTSHRMAPT | |
| SCHEMBL8082709 | 0.87 | PPARG (0.56) | PPARAPPARGTSHRLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL8074440 | 0.86 | PPARG (0.55) | PPARASMN1; SMN2PPARGTSHRLMNA | |
| SCHEMBL8074404 | 0.85 | PPARA (0.42) | PPARASMN1; SMN2PPARGTSHRMAPT | |
| SCHEMBL8074400 | 0.84 | PIN1 (0.44) | PPARATSHRLMNAKMT2ANPC1 | |
| SCHEMBL2103556 | 0.81 | PKM (0.54) | PPARASMN1; SMN2PPARGMAPTLMNA | |
| SCHEMBL8935912 | 0.81 | SMN1; SMN2 (0.49) | PPARASMN1; SMN2PPARGPTPN1 | |
| SCHEMBL8935919 | 0.81 | SMN1; SMN2 (0.49) | PPARASMN1; SMN2PPARGPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |