Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | MMP8 | P22894 | 2/20 | 0.32 |
| ▸ | MMP13 | P45452 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8087689 | 0.74 | MAOA (0.44) | MAOAMAOBGRIN1GRIN2APDE4A | |
| SCHEMBL27554766 | 0.72 | KMT2A (0.45) | KMT2AMEN1 | |
| SCHEMBL8082535 | 0.70 | KMT2A (0.40) | POLBKMT2AALDH1A1MEN1 | |
| SCHEMBL8082537 | 0.70 | KMT2A (0.40) | POLBKMT2AALDH1A1MEN1 | |
| SCHEMBL6730223 | 0.67 | GRIN1 (0.42) | POLBMAOAMAOBGRIN1GRIN2A | |
| SCHEMBL27488276 | 0.67 | MMP9 (0.54) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL6730464 | 0.66 | GRIN1 (0.43) | POLBMAOAMAOBGRIN1GRIN2A | |
| SCHEMBL14378048 | 0.65 | LMNA (0.40) | POLBMAOAMAOBGRIN1GRIN2A | |
| SCHEMBL6942322 | 0.65 | LMNA (0.40) | POLBMAOAMAOBGRIN1GRIN2A | |
| SCHEMBL31655492 | 0.64 | GRIN1 (0.38) | POLBMAOAMAOBGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6034215-A | 3-amino-2-oxo-1-piperidnercetic derivatives as enzyme inhibitors | CORVAS INTERNATIONAL, INC. (US) | 2000-03-07 | — | — | US | disclosed |
| US-5703208-A | ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. (US) | 1997-12-30 | — | — | US | disclosed |