SCHEMBL8913564

SCHEMBL8913564

NC1(Cc2ccccc2)CCCCN(C[C]=O)C1=O

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
F2 P00734 8/20 0.44
PRSS1 P07477 7/20 0.44
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
DPP4 P27487 2/20 0.39
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
F10 P00742 1/20 0.37
OPRM1 P35372 1/20 0.33
OPRL1 P41146 1/20 0.33
ELANE P08246 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8913362 0.96 F2 (0.47) F2PRSS1KMT2AMEN1DPP4
Hydrochloric Acid SCHEMBL27484359 0.78 MEN1 (0.51) F2PRSS1KMT2AMEN1DPP4
SCHEMBL8083108 0.77 F2 (0.57) F2PRSS1KMT2AMEN1MAOA
SCHEMBL3240295 0.75 HRH3 (0.50) KMT2AMEN1L3MBTL1
SCHEMBL8912826 0.72 PPIA (0.48) F2PRSS1F10
SCHEMBL24816477 0.69 MAOA (0.48) KMT2ADPP4MAOAMAOB
SCHEMBL11558761 0.69 MAOA (0.48) KMT2ADPP4MAOAMAOB
SCHEMBL9439079 0.68 OPRM1 (0.57) F2PRSS1MAOAMAOBF10
SCHEMBL4680616 0.68 KDM1A (0.39) F2PRSS1KMT2AMEN1DPP4
SCHEMBL8087689 0.66 MAOA (0.44) KMT2ADPP4MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5703208-A ANTICOAGULANTS CORVAS INTERNATIONAL, INC. (US) 1997-12-30 US disclosed