Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.95 |
| ▸ | EBP | Q15125 | 2/20 | 0.95 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.95 |
| ▸ | EBPL | Q9BY08 | 1/20 | 0.81 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.75 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8075024 | 0.99 | SIGMAR1 (0.92) | SIGMAR1EBPTMEM97EBPLABCB1 | |
| [11C]Sa4503 SCHEMBL968642 | 0.97 | SIGMAR1 (1.00) | SIGMAR1EBPTMEM97EBPLABCB1 | |
| [11C]Sa4503 SCHEMBL29358558 | 0.97 | SIGMAR1 (1.00) | SIGMAR1EBPTMEM97EBPLABCB1 | |
| [11C]Sa4503 SCHEMBL29358694 | 0.96 | SIGMAR1 (0.97) | SIGMAR1EBPTMEM97EBPLABCB1 | |
| [11C]Sa4503 SCHEMBL1299046 | 0.96 | SIGMAR1 (0.97) | SIGMAR1EBPTMEM97EBPLABCB1 | |
| Hydrochloric Acid SCHEMBL8088187 | 0.96 | SIGMAR1 (0.97) | SIGMAR1EBPTMEM97EBPLABCB1 | |
| Hydrochloric Acid SCHEMBL8075041 | 0.96 | SIGMAR1 (0.88) | SIGMAR1EBPTMEM97EBPLABCB1 | |
| SCHEMBL8953682 | 0.94 | SIGMAR1 (0.83) | SIGMAR1EBPTMEM97EBPLABCB1 | |
| SCHEMBL8086559 | 0.93 | SIGMAR1 (0.92) | SIGMAR1EBPTMEM97EBPLABCB1 | |
| Hydrochloric Acid SCHEMBL466981 | 0.92 | SIGMAR1 (0.81) | SIGMAR1EBPTMEM97EBPLABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711763-B1 | 1,4-DI(PHENYLALKYL)PIPERAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-10-18 | — | — | EP | disclosed |
| US-5736546-A | BRAIN DISORDERS; PSYCHOLOGICAL DISORDERS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0711763-A1 | NOVEL 1,4-DI(PHENYLALKYL)PIPERAZINE DERIVATIVE | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-05-15 | — | — | EP | disclosed |