[11C]Sa4503

[11C]Sa4503

SCHEMBL29358558

COc1ccc(CCN2CCN(CCCc3ccccc3)CC2)cc1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 5/20 1.00
EBP Q15125 2/20 1.00
TMEM97 Q5BJF2 1/20 1.00
EBPL Q9BY08 1/20 0.86
ABCB1 P08183 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
[11C]Sa4503 SCHEMBL968642 1.00 SIGMAR1 (1.00) SIGMAR1EBPTMEM97EBPLABCB1
[11C]Sa4503 SCHEMBL29358694 0.99 SIGMAR1 (0.97) SIGMAR1EBPTMEM97EBPLABCB1
[11C]Sa4503 SCHEMBL1299046 0.99 SIGMAR1 (0.97) SIGMAR1EBPTMEM97EBPLABCB1
Hydrochloric Acid SCHEMBL8088187 0.99 SIGMAR1 (0.97) SIGMAR1EBPTMEM97EBPLABCB1
SCHEMBL8083210 0.97 SIGMAR1 (0.95) SIGMAR1EBPTMEM97EBPLABCB1
SCHEMBL8086559 0.96 SIGMAR1 (0.92) SIGMAR1EBPTMEM97EBPLABCB1
Hydrochloric Acid SCHEMBL8075024 0.96 SIGMAR1 (0.92) SIGMAR1EBPTMEM97EBPLABCB1
Hydrochloric Acid SCHEMBL8086545 0.95 SIGMAR1 (0.90) SIGMAR1EBPTMEM97EBPLABCB1
SCHEMBL8075010 0.94 SIGMAR1 (0.89) SIGMAR1EBPTMEM97EBPL
Hydrochloric Acid SCHEMBL8074974 0.94 SIGMAR1 (0.88) SIGMAR1EBPTMEM97EBPLABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 355 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4719488-A1 EXTRACELLULAR VESICLES FOR DRUG DELIVERY AND USES THEREOF UMC Utrecht Holding B.V. (NL) 2026-04-08 EP claimed
EP-4623932-A1 AGENT FOR ALLEVIATING CLOZAPINE-INDUCED SIALORRHEA National University Corporation Chiba University (JP) 2025-10-01 EP claimed
EP-4562184-A2 THERAPY SELECTION AND TREATMENT OF NEURODEGENERATIVE DISORDERS Anavex Life Sciences Corp. (US) 2025-06-04 EP claimed
EP-4561566-A1 COMPOSITIONS AND METHODS FOR PREVENTION OF COGNITIVE DECLINE CAUSED BY DEGENERATIVE DISEASES Anavex Life Sciences Corp. (US) 2025-06-04 EP claimed
CN-119997948-A Compositions and methods for preventing cognitive decline caused by degenerative diseases 阿纳韦克斯生命科学公司 2025-05-13 CN claimed
US-20250032503-A1 USE OF APREPITANT FOR TREATING ALZHEIMER'S DISEASE HOTH THERAPEUTICS, INC. 2025-01-30 US claimed
US-20240417798-A1 THERAPY SELECTION AND TREATMENT OF NEURODEGENERATIVE DISORDERS ANAVEX LIFE SCIENCES CORP. 2024-12-19 US claimed
WO-2024248610-A1 EXTRACELLULAR VESICLES FOR DRUG DELIVERY AND USES THEREOF. UMC UTRECHT HOLDING B.V. (NL) 2024-12-05 WO claimed
CN-119004305-A Deep learning-based method for detecting abnormal industrial data under chain 桂林电子科技大学 2024-11-22 CN claimed
EP-4436573-A1 THERAPY SELECTION AND TREATMENT OF NEURODEGENERATIVE DISORDERS Anavex Life Sciences Corp. (US) 2024-10-02 EP claimed
CN-117418037-A Primer combination for rapidly detecting genotypes of multiple functional loci of peppers and application of primer combination 北京市农林科学院 2024-01-19 CN claimed
US-20230303697-A1 Antiaging effect of Intradermal Administration of Immune Checkpoint Inhibitors MYKARA, INC. (US) 2023-09-28 US claimed
US-20230263797-A1 Mammalian Hybrid Pre-Autophagosomal Structure HyPAS and Compositions and Methods for the Treatment of Coronavirus Infections and Related Disease States UNM RAINFOREST INNOVATIONS (US) 2023-08-24 US claimed
WO-2023101866-A1 FENFLURAMINE FOR TREATMENT OF CONDITIONS ASSOCIATED WITH SPREADING DEPOLARIZATION ZOGENIX INTERNATIONAL LIMITED (GB) 2023-06-08 WO claimed
WO-2023097029-A1 THERAPY SELECTION AND TREATMENT OF NEURODEGENERATIVE DISORDERS ANAVEX LIFE SCIENCES CORP. (US) 2023-06-01 WO claimed
US-20230165810-A1 FENFLURAMINE FOR TREATMENT OF CONDITIONS ASSOCIATED WITH SPREADING DEPOLARIZATION ZOGENIX INTERNATIONAL LIMITED (GB) 2023-06-01 US claimed
WO-2023034803-A1 METHODS FOR TREATMENT OF FIBROSIS THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2023-03-09 WO claimed
WO-2022169961-A1 SIGMA RECEPTOR LIGANDS FOR TREATING SARS-COV-2 INFECTION UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2022-08-11 WO claimed
US-20220226278-A1 OPTIMIZED SIGMA-1 AGONIST METHOD OF RESPONDER SELECTION AND TREATMENT ANAVEX LIFE SCIENCES CORP. (US) 2022-07-21 US claimed
US-20220023291-A1 COMPOSITIONS AND METHODS FOR REGULATING INFLAMMATION UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2022-01-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230165810-A1 FENFLURAMINE FOR TREATMENT OF CONDITIONS ASSOCIATED WITH SPREADING DEPOLARIZATION SIGMAR1, HTR1A, HTR1E SIGMAR1 1/4885EBP 1489/4885TMEM97 13/4885
US-20250032503-A1 USE OF APREPITANT FOR TREATING ALZHEIMER'S DISEASE TACR1, ACHE, TACR2 SIGMAR1 554/4885EBP 3050/4885TMEM97 2428/4885
US-20220023291-A1 COMPOSITIONS AND METHODS FOR REGULATING INFLAMMATION SIGMAR1, OPRL1, FPR1 SIGMAR1 1/4885EBP 631/4885TMEM97 255/4885
US-20230263797-A1 Mammalian Hybrid Pre-Autophagosomal Structure HyPAS and Compositions and Methods for the Treatment of Coronavirus Infections and Related Disease States SARS1, SQSTM1, ATG4A SIGMAR1 2480/4885EBP 524/4885TMEM97 655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.