SCHEMBL8083533

SCHEMBL8083533

CCOCCCOCOCC(=O)O

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
TSHR P16473 2/20 0.39
EPHX2 P34913 1/20 0.37
GLA P06280 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CES2 O00748 1/20 0.35
THRB P10828 1/20 0.34
PAM P19021 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
PTGS1 P23219 1/20 0.33
CYP2C19 P33261 1/20 0.33
KDM4E B2RXH2 1/20 0.33
HTT P42858 1/20 0.33
NPC1 O15118 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6667392 0.87 EPHX2 (0.38) TSHREPHX2CES2THRBCYP2C19
SCHEMBL30523306 0.85 ALDH1A1 (0.45) ALDH1A1TSHREPHX2GLAL3MBTL1
SCHEMBL25856021 0.83 CES2 (0.48) ALDH1A1TSHREPHX2CES2THRB
SCHEMBL25855954 0.83 CES2 (0.47) ALDH1A1TSHREPHX2GLAL3MBTL1
SCHEMBL20548069 0.83 CES2 (0.52) ALDH1A1TSHREPHX2GLAL3MBTL1
SCHEMBL1172675 0.80 ALDH1A1 (0.52) ALDH1A1TSHREPHX2GLAL3MBTL1
SCHEMBL11995924 0.79 ALDH1A1 (0.45) ALDH1A1TSHRTHRBKDM4E
SCHEMBL2865428 0.78 ALDH1A1 (0.50) ALDH1A1TSHREPHX2GLAL3MBTL1
SCHEMBL29525974 0.78 ALDH1A1 (0.50) ALDH1A1TSHREPHX2GLAL3MBTL1
SCHEMBL22609510 0.78 ALDH1A1 (0.50) ALDH1A1TSHREPHX2GLAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2000512663-A 2000-09-26 JP claimed
EP-1003469-A2 FRAGRANCE PRECURSORS GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 2000-05-31 EP claimed
WO-1997030687-A2 FRAGRANCE PRECURSORS GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1997-08-28 WO claimed