Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.60 |
| ▸ | CTSS | P25774 | 7/20 | 0.58 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083712 | 0.89 | CTSK (0.67) | CTSKCTSSHDAC4HDAC1REN | |
| SCHEMBL7372337 | 0.85 | CTSS (0.57) | CTSKCTSSCTSLCTSBREN | |
| SCHEMBL7372683 | 0.85 | CTSS (0.57) | CTSKCTSSCTSLCTSBREN | |
| SCHEMBL7369435 | 0.82 | CTSK (0.52) | CTSKCTSSCTSLCTSB | |
| SCHEMBL9300286 | 0.81 | TSHR (0.54) | CTSKCTSS | |
| SCHEMBL26436628 | 0.81 | CTSK (0.79) | CTSKCTSSCTSLCTSB | |
| SCHEMBL11120949 | 0.81 | CTSS (0.64) | CTSKCTSSCTSLCTSB | |
| SCHEMBL2118971 | 0.80 | CTSK (0.74) | CTSKCTSSCTSLCTSBHDAC4 | |
| SCHEMBL10605035 | 0.80 | CTSK (0.74) | CTSKCTSSCTSLCTSBHDAC4 | |
| SCHEMBL7371036 | 0.80 | CTSS (0.55) | CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994027958-A1 | 4-AMIDINOPHENYLSULPHONAMIDES FOR THE TREATMENT OF THROMBO-EMBOLITIC CONDITIONS | BOEHRINGER MANNHEIM GMBH (DE) | 1994-12-08 | — | — | WO | disclosed |