Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GPR88 | Q9GZN0 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8081870 | 1.00 | LMNA (0.49) | LMNAFFAR1ALDH1A1TSHRTDP1 | |
| SCHEMBL8078931 | 0.98 | LMNA (0.50) | LMNAFFAR1ALDH1A1TSHRTDP1 | |
| SCHEMBL7787462 | 0.87 | LMNA (0.63) | LMNAFFAR1ALDH1A1TSHRGPR88 | |
| SCHEMBL970564 | 0.82 | LMNA (0.72) | LMNAALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL1001111 | 0.82 | LMNA (0.72) | LMNAALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL2045144 | 0.81 | LMNA (0.50) | LMNAALDH1A1TSHRTDP1KMT2A | |
| SCHEMBL872625 | 0.80 | LMNA (0.75) | LMNAALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL2049440 | 0.79 | LMNA (0.52) | LMNAALDH1A1TSHRTDP1KMT2A | |
| SCHEMBL8083747 | 0.77 | LMNA (0.46) | LMNATDP1KMT2ACYP2D6ADRA1A | |
| SCHEMBL2046633 | 0.77 | MAPT (0.47) | LMNAALDH1A1TSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6137008-A | USEFUL AS STARTING MATERIAL FOR MAKING FLEXIBLE AROMATIC POLYAMIDES OR POLYIMIDES | NATIONAL SCIENCE COUNCIL (TW) | 2000-10-24 | — | — | US | disclosed |
| US-5817741-A | HEAT RESISTANCE; MELT PROCESSABILITY | NATIONAL SCIENCE COUNCIL (TW) | 1998-10-06 | — | — | US | disclosed |