Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 9/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.37 |
| ▸ | PDE4A | P27815 | 6/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.37 |
| ▸ | PPOX | P50336 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9620075 | 0.92 | SCN9A (0.41) | SCN9APDE4DPDE4APDE4BPDE4C | |
| SCHEMBL9835450 | 0.85 | NPSR1 (0.43) | TSHR | |
| SCHEMBL8998058 | 0.83 | LMNA (0.34) | RORCTSHR | |
| SCHEMBL7931893 | 0.83 | SCN9A (0.52) | SCN9APDE4DPDE4APDE4BPDE4C | |
| SCHEMBL9427372 | 0.83 | LMNA (0.34) | TSHR | |
| SCHEMBL9834362 | 0.83 | LMNA (0.34) | RORCTSHR | |
| SCHEMBL9835444 | 0.83 | RORC (0.39) | PPOXRORCTSHR | |
| SCHEMBL8083764 | 0.82 | SCN9A (0.54) | SCN9APDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7922423 | 0.79 | SCN9A (0.48) | SCN9APDE4DPDE4APDE4BPDE4C | |
| SCHEMBL8191955 | 0.79 | SCN9A (0.46) | SCN9APDE4DPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496347-B1 | Methods of preparing fluorobenzene derivatives and related compounds | SAGAMI CHEM RES (JP) | 1996-09-04 | — | — | EP | disclosed |
| US-5391807-A | Methods of preparing fluorobenzene derivatives and related compounds | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1995-02-21 | — | — | US | disclosed |
| US-5344953-A | Fluorobenzene derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1994-09-06 | — | — | US | disclosed |
| US-5281742-A | Bis(fluorophenyl) carbonate derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1994-01-25 | — | — | US | disclosed |
| EP-0496347-A2 | Methods of preparing fluorobenzene derivatives and related compounds | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-07-29 | — | — | EP | disclosed |