SCHEMBL8083889

SCHEMBL8083889

CC(C)c1c(Cl)cc([N+](=O)[O-])c(O)c1Cl

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 7/20 0.58
ALDH1A1 P00352 4/20 0.43
MEN1 O00255 4/20 0.43
MAPT P10636 4/20 0.43
KMT2A Q03164 4/20 0.43
TDP1 Q9NUW8 4/20 0.43
KDM4E B2RXH2 3/20 0.43
HTT P42858 3/20 0.43
PKM P14618 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
LMNA P02545 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
HSP90AA1 P07900 1/20 0.43
OPRK1 P41145 1/20 0.43
CYP3A4 P08684 1/20 0.41
TTR P02766 2/20 0.41
ALOX15 P16050 2/20 0.41
ALOX12 P18054 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8082917 0.84 GPR35 (0.51) GPR35ALDH1A1MEN1MAPTKMT2A
SCHEMBL10801459 0.84 GPR35 (0.48) GPR35ALDH1A1TDP1CYP3A4ALOX15
SCHEMBL31053019 0.80 GPR35 (0.74) GPR35ALDH1A1MEN1MAPTKMT2A
SCHEMBL6010888 0.79 GPR35 (0.61) GPR35ALDH1A1MEN1MAPTKMT2A
SCHEMBL9112380 0.77 GPR35 (0.83) GPR35ALDH1A1MEN1MAPTKMT2A
SCHEMBL10599797 0.75 GPR35 (0.49) GPR35ALDH1A1MEN1MAPTKMT2A
SCHEMBL12985496 0.75 TDP1 (0.60) ALDH1A1TDP1CYP3A4HPGDMAPK1
SCHEMBL10599169 0.75 GPR35 (0.56) GPR35ALDH1A1MEN1MAPTKMT2A
SCHEMBL6815361 0.75 GPR35 (0.56) GPR35ALDH1A1MEN1MAPTKMT2A
SCHEMBL8082966 0.75 GPR35 (0.56) GPR35ALDH1A1MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0608896-B2 Process for producing aromatic amide compounds useful as cyan coupler for color photographs SUMITOMO CHEMICAL CO (JP) 2000-11-02 EP disclosed
US-5442114-A Process for producing aromatic amide compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-08-15 US disclosed
EP-0473464-B1 Process for preparing 2-4-dichloro-3-alkyl-6-nitrophenols TAOKA CHEMICAL CO LTD (JP) 1995-06-14 EP disclosed
EP-0608896-A1 Process for producing aromatic amide compounds useful as cyan coupler for color photographes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-08-03 EP disclosed
US-5136109-A PROCESS FOR PREPARING 2,4-DICHLORO-3-ALKYL-6-NITROPHENOLS TAOKA CHEMICAL COMPANY, LTD. (JP) 1992-08-04 US disclosed
EP-0473464-A1 Process for preparing 2-4-dichloro-3-alkyl-6-nitrophenols TAOKA CHEMICAL CO., LTD (JP) 1992-03-04 EP disclosed
US-5012015-A Nitrading a trichlorobenzene with mixed acid, hydrolysis DAIEI CHEMICAL CO., LTD. (JP) 1991-04-30 US disclosed
EP-0175151-B1 2,4-DICHLORO-3-ALKYL-6-NITROPHENOLS AND PROCESS FOR THEIR PREPARATION BAYER AG (DE) 1989-01-18 EP disclosed
US-4670608-A CATALYTIC CHLORINATION OF 1-ALKYL-4-NITROBENZENE BAYER AKTIENGESELLSCHAFT (DE) 1987-06-02 US disclosed
EP-0175151-A1 2,4-Dichloro-3-alkyl-6-nitrophenols and process for their preparation BAYER AG (DE) 1986-03-26 EP disclosed